IJAR.2021.196

Type of Article:  Case Report

Volume 10; Issue 1 (March 2022)

Page No.: 8250-8254

DOI: https://dx.doi.org/10.16965/ijar.2021.196

Craniocerebral and Spinal Dysraphism with Omphalocele – A Case Report of Primary Neurulation Defect

Rahe Rajan *1, Wms Johnson 2, Krishnaveni Sharath 3, Durga Devi G 4, Jinu Merlin Koshy 5.

*1 Associate Professor, Department of Anatomy, Sree Balaji medical college and hospital, BIHER, Chrompet, Chennai, India. https://orcid.org/0000-0002-0487-0412

2 Professor, Department of Anatomy, Sree Balaji medical college and hospital, Chrompet, Chennai, India. https://orcid.org/0000-0002-2522-3783

3 Associate Professor, Department of Anatomy, Sree Balaji medical college and hospital BIHER, Chrompet, Chennai, India. https://orcid.org/0000-0001-7714-5804

4 Associate Professor, Department of Anatomy, Sree Balaji medical college and hospital, BIHER, Chrompet, Chennai, India. https://orcid.org/0000-0003-1852-8711

5 Associate Professor, Department of Anatomy, Sree Balaji medical college and hospital, BIHER, Chrompet, Chennai, India. https://orcid.org/0000-0002-2072-6576

Corresponding Author: Dr Rahe Rajan, Associate professor, Department of Anatomy,  Sree Balaji Medical College, Bharath Institute of higher education and Research, No 7, C.L.C Works Road, Chrompet, Chennai, 600044 Tamil Nadu, India. Tel: 9944072470    E-Mail: drrahee12@gmail.com   

ABSTRACT

Background: Anencephaly and Spina bifida are the two most common types of neural tube defects (NTDs). Disrupted formation and closure of neural folds leads to Craniocerebral and spinal dysraphisms.

Materials and methods: An 18 week old foetus was received in the department of Anatomy after elective medical termination of pregnancy due to the diagnosis of neural tube defect and associated congenital anomalies.

Case Report: The foetus had anencephaly, thoracic-lumbar spina bifida, omphlocele and clubbed foot and hands. The foetus was dissected and studied, to look for abnormal internal structures. On meticulous dissection it was found that there were abnormalities in spine, gastrointestinal system and cranium.

Conclusion: Anencephaly is a neural tube defect which has multiple neural and non-neural associated anomalies. A detailed description of the combination of associated anomalies goes a long way in updating knowledge on the same.

Key words: Anencephaly, spina bifida, omphalocele, folic acid, neural tube defects.

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Cite this article: Rahe Rajan, WMS Johnson, Krishnaveni Sharath, Durga Devi G, Jinu Merlin Koshy. Craniocerebral and Spinal Dysraphism with Omphalocele – A Case Report of Primary Neurulation Defect. Int J Anat Res 2022;10(1):8250-8254. DOI: 10.16965/ijar.2021.196