Type of Article:  Original Research

Volume 8; Issue 2.1 (April 2020)

Page No.: 7424-7429

DOI: https://dx.doi.org/10.16965/ijar.2020.120


Vaishali Sitaram Kirwale 1, S. S. Dhapate *2.

1 Assistant Professor, Department of Anatomy, Government Medical College, Aurangabad, Maharashtra, India.

*2 Professor and Head, Department of Anatomy, S.R.T.R Medical College,  Ambajogai, Beed, Maharashtra, India.

Corresponding Author: Dr. Shankar S. Dhapate, Professor and Head, Department of Anatomy, S.R.T.R Medical College Ambajogai, Beed, Maharashtra, India. E-Mail: anasrtr@rediffmail.com


Introduction: Thymus consists of two pyramidal lobes. It is located in the mediastinum behind the sternum and in front of the pericardium and great vessels of the heart. The present study has been undertaken to highlight some important points in morphometry of foetal thymus gland.

Materials and Methods: In the present study 30 foetuses (12-38 week) were studied. The obtained foetuses were fixed in 10% formalin. After proper fixation they were subjected to dissection. The length and breadth of gland was measured by vernier caliper in centimeters. Weight of the gland was measured using electronic weighing machine. Naked eye examination done for number of lobes.

Results: The average length of the thymus at 12th week was 0.2cm on right side and 0.2cm on left side, it was increased to 4cm on right side and 4.5cm on left side. The average breadth of thymus was 0.12cm on right side and 0.10cm on left side at 12th week which was increased to 2.2cm and 2.6cm on right & left side respectively at 38th week. The average weight of thymus was 0.1 gm at 12th week and 8.2 gm at 38th week. The majority of thymus 26(86.67%) shows presence of two lobes.

Conclusion: All parameters length, breadth and weight of thymus show gradual increase with advancing gestational age with significant changes. There are wide variations in number of lobes of thymus gland.

Key words: Thymus, morphometry, foetuses, gestational age.


  1. Moore KL, Persaud. The Developing human: clinically oriented embryology 8th ed. Philadelphia: W. B. Saunders Company; 2008. p. 179.
  2. Galen on the usefulness of the parts of the body Ithaca. Cornell University Press (New York) 1968: 30.
  3. Mizuki Nishino, Simon K. Ashiku, Olivier N. Kocher, Robert L. Thurber, Phillip M. Boiselle, HirotoHatabu. The Thymus: A comprehensive Review. Radio Graphics 2006; 26: 335-348.
  4. Arey LB. Developmental anatomy. 6th Philadelphiaand London: WB Saunders company;1956:  21-23, 234-236.
  5. Seid Abbas Tabatabaie, Seid Mozafar Hashemi, Behnam Sanei, Mohammad Hossein Sanei, The frequency of ectopic thymic tissue in the necks of patients without any thymic disease, © Med Sci Monit, 2007; 13(6): CR283-285
  6. Goldstein G, Scheid M P, Boyse E A, Schlesinger D H, van Vauwe J.(1979).A synthetic pentapeptide with biological activity characteristic of the thymic hormone thymopoietin. Science 204: 1309–1310.
  7. Nowak PA, Zarbo RJ, Jacobs JR: Aberrant solid cervical thymus. Ear Nose Throat J, 1988; 67: 670
  8. Krishna Murthy,V.Subadra Devi. Morphological features of human thymus gland from foetal to old age. International journal of biological and medical research. 2010; 3(2):1502-1505.
  9. Standring S, Borely NR, Collins P, Crossman AR, Gatzzoulis MA, Healy JC, et al. Gray’s Anatomy. 40th Chrchill Livingstone Elsevier publisher; 2008.p. 945-49.
  10. Hasselbalch H, Jeppesen DL, Engelmann MDM, Michaelsen KF & Nielsen MB(1995). Decreased thymus size in formula-fed infants compared with breastfed infants. Acta Paediatrica 85: 1029–1032.
  11. Vijaya Lakshmi, B. Narasinga Rao and M. Pramila Padmini. Histo-Morphogenesis of Thymus in Human Foetuses. International Jouranal of Basic and Applied Medical Sciences.2012: 2(2):78-82.
  12. Mamta Rani, Nityanand Srivastava, Anuj Jain, Adil ashgar. Study of Morphological Features of Thymus Gland In Human Foetuses At Different Age Group IOSR Journal of Dental and medical Sciences (IOSR-JDS); 17(7), 2018: 31-37.
  13. Yekeler E, Tambag A, Tunaci A, Genchellac H, Dursun M, Gokcay G, Acunas G. Analysis of the thymus in 151 healthy infants from 0 to 2 years of age. Ultrasound Med 2004;23(10):1321–1326
  14. Dubey Aksh, Jethani SL, Singh Deepa. A Study of Correlation between Transverse diameter of fetal thymic lobes and gestational age. International Journal of Research in health Sciences. 2014;2(2)715-719.

Cite this article: Vaishali Sitaram Kirwale, S. S. Dhapate. MORPHOMETRIC STUDY OF HUMAN FOETAL THYMUS. Int J Anat Res 2020;8(2.1):7424-7429. DOI: 10.16965/ijar.2020.120