Type of Article:  Original Research

Volume 8; Issue 1.3 (March 2020)

Page No.: 7408-7411

DOI: https://dx.doi.org/10.16965/ijar.2020.115


K. Satheesh Naik 1,   Sadhu Lokanadham *2, M Gurushanthaiah 3.

1 Assistant Professor, Department of Anatomy, Viswabharathi Medical College, Penchikalapadu, Kurnool, Andhrapradesh, India.
*2 Associate Professor, Department of Anatomy, Santhiram Medical College, Nandyal, Andhrapradesh, India.
3 Professor, Department of Anatomy, Basaveshwara Medical College, Chitradurga, Karnataka, India.

Corresponding Author: Dr.Sadhu Lokanadham, Associate professor, Department of anatomy, Santhiram Medical College, Nandyal, Andhrapradesh – 518501. Contact No: +919542093368 E-Mail: nsatheesh43@gmail.com; drsadhuln.anatomy@gmail.com


Introduction: Liver is an important gland of gastrointestinal tract having both exocrine and endocrine functions and it is having the extensive power of regeneration. Not only the adult liver, the foetal liver is an important organ with synthetic and haemopoietic functions. It develops as a ventral outgrowth During 3rd week of gestational age from the gut endoderm in the region of the anterior intestinal portal.

Materials and Methods: We used Total of 27 formalin Preserved dead embryos and foetuses from 5weeks to 40 Weeks of gestational age of both the sexes with relevant obstetric records available in the department of Anatomy, Viswabharathi Medical College, Penchikalapadu, Kurnool for this study.

Results: In the present study a total of 27 aborted embryos and foetuses of different gestational ages of both sexes of normal  and abnormal were observed (table -1). The liver specimens are categorized in to gestational age groups of 0 – 12 weeks, 12 – 24 weeks, 24 – 36 weeks and more than 36 weeks.

Conclusion: At 5-6weeks of gestational age we observed the aggregation of hepatocytes and early stage of haemopoiesis which is in agreement with literature. Delay in the Histogenesis and development of the liver cells and bile duct system leads to histopathological and developmental abnormalities gives knowledge to the clinicians during clinical procedures.

Key words: Binucleated Hepatocytes, Kupffer cells, sinusoids.


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Cite this article: K. Satheesh Naik, Sadhu Lokanadham, M Gurushanthaiah. DIFFERENT GESTATIONAL AGE RELATED HISTOGENESIS OF HUMAN FOETAL LIVER. Int J Anat Res 2020;8(1.3):7408-7411. DOI: 10.16965/ijar.2020.115