Type of Article:  Original Research

Volume 7; Issue 4.1 (October 2019)

Page No.: 7003-7006

DOI: https://dx.doi.org/10.16965/ijar.2019.285


Maitreyee M.Kulkarni 1, Jagdish S.Soni *2, Shital Bhishma Hathila 3.

1  Maitreyee M Kulkarni M.Sc  Medical Anatomy, Medical College Baroda, Gujarat, India.

*2 Dr.Jagdish S.Soni, M.S.Anatomy, Associate Professor, Anatomy Department, Medical College, Baroda, Gujarat, India.

3 Assistant Professor, Anatomy Department, Medical College, Baroda, Gujarat, India.

Corresponding Author: Dr.Jagdish S.Soni, P-13, Aviral Society, Opposite Mangalam Duplex, Sama-Savli Road, Baroda, Gujarat-390024 Mobile:09426587464 E-Mail: ashushiti@yahoo.co.in


Background: Hippocampus is one of the key parts of limbic system. It is located in the floor of the inferior horn of lateral ventricle.

Materials and methods: The study is conducted on 50 Hippocampi removed from 25 cadaveric brains in Medical College Baroda, Gujarat. The volume of each is measured by water displacement method.

Results: It is observed that the mean volume for the sample is 2.26+0.88cc. The mean volume on right side is 2.37+0.88cc and on the left side is 2.12+0.88cc. The mean volumes seen in male and female hippocampi are 2.14+0.70cc and 2.52+1.21cc respectively. The mean volume in the age group 60-80 years is 2.55+0.65cc and in the age group 81 years onwards, it is 2.0+1.03cc. The difference in volumes of the two age groups is found to be statistically significant. Conclusion: The study will be useful to anatomists, Neurologists, Neurosurgeons and psychiatrists alike.

Key words: Hippocampus, limbic system, Volume, age.


  1. Barrs’s The Human Nervous System: An Anatomical Viewpoint by John Kiernan and Raj Rajakumar in chapter 18, 10th edition; Pg 323-38.
  2. Gray’s Anatomy The Anatomical basis of Clinical Practice by Susan Standring in chapter 23, 40th edition; Pg 335-60.
  3. Destrieux, D.Bourry, S.Velut Surgical Anatomy of Hippocampus. Neurochirurgie 2013;59:149-158.
  4. Sven Dekeyzer & Isabelle De Kock & Omid Nikoubashman, Stephanie Vanden Bossche & Ruth Van Eetvelde & Jeroen De Groote & Marjan Acou & Martin Wiesmann & Karel Deblaere & Eric Achten  B; Unforgettable – a pictorial essay on anatomy and pathology of the hippocampus. Insights Imaging 2017;8:199–212.
  5. Rajmohan V, Mohandas E. The limbic system. Indian Journal of Psychiatry 2007;49(2):132- 139.
  6. Grant’s Dissector by Patrick. W. Tank; Lippincott Williams & Wilkins, 15th Edition;306-308.
  7. Rao B, Prasad Rao K, Rao R. Morphometric Study Of Hippocampus In Adult Human Brains. International Journal of basic and applied Basic sciences,2012;2(2):139-143.
  8. Yucel K, Hakyemez B, Parlak M Morphometry of some elements of limbic system in normal population: a quantitative MRI study. Neuroanatomy, 2002;1:15-21.
  9. Watson, MD, PhD; F. Andermann, MD, FRCP(C); P. Gloor, MD, PhD; M. Jones-Gotman, PhD; T. Peters, PhD; A. Evans, PhD; A. Olivier, MD, PhD, FRCS(C); D. Melanson, MD; and G. Leroux, RT Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging; NEUROLOGY 1992;42: 1743-1750.
  10. Delgado-González JC, Mansilla-Legorburo F,Florensa Vila J, Insausti A M, Viñuela A,Tuñón Alvarez T, et al. Quantitative Measurements in the Human Hippocampus and RelatedAreas: Correspondence between Ex-Vivo MRI and Histological Preparations. PLoSONE 2015;10(6): e0130314. doi:10.1371/ journal.pone.0130314
  11. Goran Simic, Ivica Kostovic, Bengt Winblad, And Nenad Bogdanovic Volume And Number Of Neurons Of The Human Hippocampal Formation In Normal Aging And Alzheimer’s Disease. The Journal Of Comparative Neurology 1997;379:482–494.
  12. R. S. Prasad Rao. CYTOARCHITECTURE OF HUMAN ADULT HIPPOCAMPUS. Int J Anat Res 2016;4(3):2764-2770. DOI: 10.16965/ijar.2016.330

Cite this article: Maitreyee M.Kulkarni, Jagdish S.Soni, Shital Bhishma Hathila. A VOLUMETRIC STUDY OF HIPPOCAMPUS IN CADAVERIC HUMAN BRAINS. Int J Anat Res 2019;7(4.1):7003-7006. DOI: 10.16965/ijar.2019.285