IJAR.2019.275

Type of Article:  Original Research

Volume 7; Issue 4.1 (October 2019)

Page No.: 6996-7002

DOI: https://dx.doi.org/10.16965/ijar.2019.275

COMPUTED TOMOGRAPHY BASED PANCREATIC VOLUME MEASUREMENT IN KASHMIRI POPULATION

Gousia Nisa 1, Bashir Ahmad Shah 2, Snobar Gul *3, Shabir Ahmad Bhat 4.

1 Demonstrator, Department of Anatomy, Government Medical College, Srinagar, J&K, India.

2 Associate Professor, Department of Anatomy, Government Medical College, Srinagar, J&K, India.

*3 Demonstrator, Department of Anatomy, Government Medical College, Srinagar, J&K, India.

4 Associate Professor, Department of Radiodiagnosis & Imaging, Government Medical College, Srinagar, J&K, India.

Corresponding Author: Dr Snobar Gul, Demonstrator, Department of Anatomy, Government Medical College, Srinagar, J&K, India. E-Mail: snobaryounis@gmail.com

ABSTRACT:

Background: The volume of various abdominal organs varies with age, height, weight and body mass index (BMI). Scanning of the viscera is carried out to know the normal dimensions and volumes. Studies have shown that the volume of pancreas is influenced by age, gender, ethnicity, weight, height and BMI. Organ volume and function reflect the health of the organs. Altered volume of pancreas is associated with infective, infiltrative, immunological, infestative and malignant conditions. Anthropometry varies with races and regions of the world. Specific ethnic population nomograms are needed for proper medical diagnosis and for monitoring disease progress.

Results: A total of 300 eligible subjects between 20-60 years of age, who were to undergo abdominal computed tomography (CT) due to various indications, were included in the study. In our study the mean pancreatic volume (PV) was 115.71+-33.60 cm3. Pancreatic volume was significantly correlated with weight, height and BMI of the subjects in our study.

Conclusion: Nomograms from this data can be used locally for Kashmiri ethnic population to allow clinicians to estimate more accurately the degree of atrophy or hypertrophy of organs in certain disorders and thus, avoid false positive and false negative diagnosis of pathological enlargement or reduction of pancreas in clinical practice.

Key words: Computed tomography, Pancreatic volume, BMI.

REFERENCES

  1. Standring S. Pancreas. Gray’s Anatomy. The Anatomical Basis of Clinical Practice. 41st Churchhill Livingstone. Edinburg London New York.2008;205-216.
  2. Caglar V, Ozen OA, Uygur R, Sedaroglu O, Alkoc OA. Determination of normal splenic volume in relation to age, gender and body habitus: a stereological study on computed tomography.Folia Morphol.2014; 73(3): 331-338.
  3. Djuric-Stefanovic A, Masulovic D, Kostic J, Randjic K & Saranovic D: CT volumetry of normal pancreas: correlation with the pancreatic diameters measurable by cross-sectional imaging and relationship with gender, age and body constitution . Surg Radiol Anat (2012) 34:811-817.
  4. Prassopoulos P, Daskalogiannaki M, Raissaki M, Hatjidakis A, Gourtsoyiannis N. Determination of normal splenic volume on computed tomography in relation to age, gender and body habitus. European Radiology.1997;7:246-248.
  5. Geraghty EM, Boone JM, McGahan JP, Jain K. Normal organ volume assessment from abdominal CT.Abdom Imaging,2004;29:482-490.
  6. Heuck A, Maubach PA, Reiser M, Feuerbach S, Allgayer B, Lukas P, KahnT. Age related morphology of the normal pancreas on computed tomography. Gastrointest Radiol.2004;12:18-22.
  7. Balthazar EJ, Megibow AJ, Pozzi Mucelli R. Imaging of the pancreas. Acute and chronic pancreatitis. 2009; Springer, Berlin.
  8. Morgan DE, Stanley RJ. The pancreas in: Lee JK, Sagel SS, Stanley RJ, Haiken JP(eds) Computed body Tomography with MRI correlation. 2006; Lippincott Williams and Wilkins, Philadelphia:1016-1017.
  9. Saisho Y, Butler AE, Meir JJ et al. Pancreatic volumes in humans from birth to one hundred taking into account sex, obesity and presence of type2 diabetes. Clin Anat.2007;20:933-942.
  10. Alzaid A, Aideyan O, Nawaz S. The size of the pancreas in diabetes mellitus. Diabet Med.1993;10:759-763.
  11. Goda K, Sasaki E, Nagata K, Fukai M, Ohsawa N, Hahafusa T. Pancreatic volume in type1 and type 2 diabetes mellitus. Acta Diabetol.2001;38:145-149.
  12. Sakata N, Egawa S, Rikiyama T et al. Computed tomography reflected endocrine function of the pancreas. J Gastrointest surg.2011;525-532.
  13. Vesterhus M, Haldorsen IS, Reader H, Molven A, Njolstal PR. Reduced pancreatic volume in hepatocyte nuclear factor IA-maturity onset diabetes of the young. J Clin Endocrinol Metab.2008;93:3505-3509.
  14. Standring S. Pancreas. Gray’s Anatomy. The Anatomical Basis of Clinical Practice.39thChurchhill Livingstone. Edinburg London New York.2005;1231-7.
  15. Paredes JL, Orabi AI, Ahmad T, Benbourenane I, et al. A non-invasive method of quantifying pancreatic volume in mice using micro-MRI. 2014; Plos ONE 9(3): e92263.
  16. Gurda GT, Crozier SJ, Ji B, Ernst SA, Logsdon CD, et al. (2010) Regulator of calcineurin 1 controls growth plasticity of adult pancreas. Gastroenterology 139: 609-619.
  17. El-Hodhod MA, Nassar MF, Hetta OA, Gomaa SM. Pancreatic size in Protein Energy Malnutrtion: a predictor of nutritional recovery. European J Clin Nutr.2005;59:467-73.
  18. Sprogoe-Jakobsen S, Sprogoe-Jakobsen U. The weight of the normal spleen. Forensic science International .1997;88:215-223.
  19. Batra AK, Dongre AP, Mohanty AC. A study of organ weight from persons who died in accident in Nagpur district of Maharastra state. JFMT.2002;19:21-24
  20. Sheikhazadi A, Sadr SS, Ghadyani MH, Taheri SK, Manouchehri AA, Nazparvar B, Mehrpour O, Ghorbani M. Study of the normal internal organ weights in Tehran’s population. Journal of Forensic and Legal Medicine.2010;17:78-83.
  21. Kratzer W, Fritz V, Mason RA, Haenle MM, KaecheleV and the Roemerstein Study Group: Factors affecting liver size; A sonographic survey of 2080 subjects. J Ultrasound Med2003;22: 1155-1161.
  22. Schulz HG, Christou.A, Gursky.S, Rother.P. Computerised tomography studies of normal morphology and volumetry of parenchymatous epigastric organs in humans:Anatomischer Anzeiger (1986), 162(1):1-12.
  23. Caglar V, Songur A, Yagmurca , Acar M, Toktas M, Gonul Y. Age-related volumetric changes in pancreas: a stereological study on computed tomography. 2012;34:935-941.
  24. Williams AJK, Chau W, Callway MP, Dayan CM. Magnetic Resonance Imaging: a reliable method for measuring pancreatic volume in type1 diabetes. Diabet Med.2007;24:35-40.
  25. Westermark P, Wilander E. The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus. Diabetologia.1978;15:417-421.
  26. Lohr M, Kloppe G. Residual insulin positivity and pancreatic atrophy in relation to duration of chronic type1DM and microangiopathy. Diabetologia.1987;30:757-762.
  27. Caglar V, Kumral B, Uygur R, Alkoc OA, OzenOA, DemireH. Study of Volume, Weight and Size of Normal Pancreas, Spleen and Kidney in Adults Autopsies. Forensic Medicine and Anatomy Research.2014; 2:63-69.
  28. Grandmaison GL, Clairand I, Dirigon M. Organ weight in 684 adult autopsies: New tables for a Caucasoid population. Forensic Science International.2001;119:149-154.
  29. Kou K, Saisho Y, Jinzaki M, Itoh H. Relationship between Body Mass Index and pancreas volume in Japanese adults.JOP. 2014;15(6):626-627.

 

Cite this article: Gousia Nisa, Bashir Ahmad Shah, Snobar Gul, Shabir Ahmad Bhat. COMPUTED TOMOGRAPHY BASED PANCREATIC VOLUME MEASUREMENT IN KASHMIRI POPULATION. Int J Anat Res 2019;7(4.1):6996-7002. DOI: 10.16965/ijar.2019.275