IJAR.2019.246

Type of Article:  Original Research

Volume 7; Issue 3.2 (August 2019)

Page No.: 6868-6870

DOI: https://dx.doi.org/10.16965/ijar.2019.246

CORTICAL FOLDING ON MEDIAL SURFACE OF FOETAL BRAIN AT DIFFERENT GESTATIONAL AGE

Gayatri. N *1, H.R.Sarada Sharma 2.

*1 Associate Professor of Anatomy, MNR Medical College and Hospital, Sangareddy, Telangana, India.

2 Assistant Professor of Anatomy,MNR Medical College and Hospital, Sangareddy, Telangana, India.

Address for Correspondence:Dr. Gayatri. N, Associate Professor of Anatomy, MNR Medical College and Hospital, Sangareddy, Telangana, India. Mobile no: +919866084854. E-Mail: drgayatri1884@gmail.com

ABSTRACT:

Background: Cortical folding is a hallmark of many but not all mammalian brains. The degree of folding gradually increases with the size of brains in mammals but at different range between the families.Gyrification is a process which varies widely in mammals in early foetal and prenatal life.

Materials: This study was conducted on 100 dead foetuses in anatomy department, brought from the department of Obstetrics and gynaecology of MNR Medical College and Hospital.

Results: The brain surface is smooth up to 12 weeks,Cingulate sulcus appeared by 16-18weeks.Growth of adjoining lobes of brain make surface more convoluted with well-defined sulci and gyral pattern between 30-32 weeks.

Conclusion: Cortical folding is due to consequence of restricted space and rapid growth of brain with in the cranial cavity. There is no differences between male and female brains of same gestational age, with no obvious asymmetrical development of gyri on different lobes of brain.

KEY WORDS: Cortical folding, gyrfication, Gestational age, convolutions.

REFERENCES

  1. Behnke, M. Rettmann, D. Pham, D. Shen, S. Resnick, et al. “Automatic classification of sulcal regions of the human brain cortex using pattern recognition,” in Proc. SPIE’s Medical Imaging, San Diego, CA.2003;Feb. 15-20.
  2. I. Moore. The developing human clinical oriented embryology.2008;396-404
  3. Catherine Garel, Emmanuel Chantrel et al. Fetal cerebral cortex: Normal gestational landmarks identified using prenatal MR imaging; American Journal of Neuroradiology. 2001; 22:184-189.
  4. Gregory E. Antonio, Winnie C.W.Chu, David K.W.Yeung, Anil T Ahuja. Imaging of the developing brain; Neuroembrology& aging. 2008; 5:23-31.
  5. Hughey: Military Obstetrics &Gynecology. Brookside Associates Medical Education Division. 2009; 395.
  6. J. Romanes. Cunningham Manual of Practical Anatomy, Head and neck and brain.1986; 39:43-44.
  7. Development of Nervous system. Henry Gray’s 39th edition, London; Elsevier Churchill & Livingstone P, 2005:266.
  8. I. Savel’ev. Variability of sulci and gyri in the inferior parietal Region of the human during ontogeny. Neuroscience & Behavioural Physiology.1984; 14(1):60-63.
  9. . Chi JG, Dooling EC, Gilles FH. Gyral development of the human Brain. Ann Neurol.1977; 1:86-93.
  10. Afif, R. Bouvier, A. Bunerd, J. Trouillas and P. Mertens: Development of the human fetal insular cortex: study of the gyration from 13 to 28 gestational weeks. Brain Structure and Function.2010; 212(3-4):335-346.

Cite this article: Gayatri. N, H.R.Sarada Sharma. CORTICAL FOLDING ON MEDIAL SURFACE OF FOETAL BRAIN AT DIFFERENT GESTATIONAL AGE. Int J Anat Res 2019;7(3.2):6868-6870. DOI: 10.16965/ijar.2019.246