Type of Article:  Original

Volume 7; Issue 1.3 (March 2019)

Page No.: 6307-6310

DOI: https://dx.doi.org/10.16965/ijar.2019.106


Geetha Jayachandran.

Assistant Professor, Department of Anatomy, Government Medical College, Manjeri, Malappuram (Dist), Kerala, India.

Corresponding author address: Dr Geetha Jayachandran, Assistant Professor, Department of Anatomy, Government Medical College, Manjeri-676121, Malappuram (Dist), Kerala, India. Mobile No:+91-7989240468 E-Mail: sarathgrey@gmail.com


Background: The pituitary gland (PTG) size, shape will change according to the age in response to the changes in the hormonal environment. Hence care should be taken while evaluating the PTG disorders. This present study conducted to evaluate the morphological changes in PTG with relation to age.

Materials and Methods: This study was conducted in the Department of Anatomy was approved by Institutional Human Ethics Committee. A total of 73 PTG specimens were included in this study. They are divided in to six groups based on the age. G-I (Foetus), G-II (1-10 Y), G-III (11-30 Y), G-IV (31-50 Y), G-V (51-70 Y) and G-VI(Above 71 Y). All the specimens were subjected for H&E stain. The slides were observed for morphological changes. The data was expressed in MEAN±SD and Statistical Package for Social Sciences (SPSS 16.0) version used for analysis.

Results: More number of males was in group-V and females in group-IV. Pars intermedia had maximum thickness in foetal life. Basophilic zone was not seen in foetal life but it is more prominent in other age groups. Cellularity increased as age progress. Pars anterior and nervosa showed more vascularity compared to interior. As age progress this vascularity is decreased.

Conclusion: From the study observations it can be concluded that as age progress there is a significant changes in the PTG morphology. Knowledge about these changes can useful for the diagnosis and treatment of various disorders of PTG.

Key words: Morphology, Endocrine disorders, pituitary gland, Haematoxylin & Eosin.


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Cite this article: Geetha Jayachandran. COMPARISON OF MORPHOLOGICAL CHARACTERISTICS OF PITUITARY GLAND BETWEEN THE DIFFERENT AGE GROUPS. Int J Anat Res 2019;7(1.3):6307-6310. DOI: 10.16965/ijar.2019.106