IJAR.2018.396

Type of Article:  Original Research

Volume 6; Issue 4.3 (December 2018)

Page No.: 6014-6017

DOI: https://dx.doi.org/10.16965/ijar.2018.396

THE STUDY OF CLEFT LIP AND PALATE IN NORTH KARNATAKA REGION

Dinanath Pujari 1, Sundip Charmode *2,  HS Kadlimatti 3.

1 Associate Professor, Department of Anatomy, ESIC Medical college Kalaburagi, Karnataka, India.

*2 Assistant Professor, Department of Anatomy, ESIC Medical college Kalaburagi, Karnataka, India.

3 Professor, Department of Anatomy, ESIC Medical college Kalaburagi, Karnataka, India.

Corresponding author -Sundip Charmode, Department of Anatomy, Assistant Professor, ESIC Medical College Kalaburagi, Karnataka, India.

E-Mail: sundip.charmode@yahoo.com

ABSTRACT:

Background: A cleft occurs when certain body parts and structures do not fuse together during fetal development. Clefts can involve the lip and/or the roof of the mouth (palate). There are varying opinions on the actual incidence of clefts. Some experts say that the highest cleft incidences are among Asians. As there are very few studies regarding the incidence of cleft lip and palate in North Karnataka, this study was conducted.

Materials and Methods: The data was collected from the patients of the hospital of ESIC Medical College Kalaburagi, Karnataka, India.

Result: The occurrence of cleft lip was more compared to, in combination with cleft palate and cleft palate alone. The exact cause of cleft lip and palate is not known but most experts agree that the causes of cleft lip and/or palate are multifactorial and may include a genetic predisposition, as well as environmental or nutritional factors. In this study the type of malformation, the difference in the gender of patients, the parental age during marriage and the consanguineous marriage are studied in detail. The Malformations were more on the left side compared to right side. This anomaly was observed more in male patients than female patients.

Conclusion: As the parental age is one of the predisposing factor. In this study the age of parents was found less than Twenty years in most of the cases. The consanguineous marriage is also considered as one of the risk factor, this study found that most of the parents had consanguineous marriage.

Key words: Consanguinity, Cleft Lip, Cleft Palate.

REFERENCES

  1. Banerjee and Dhakar, CLEFT LIP AND PALATE. CIBTech Journal of Surgery Review Article 2013;2(1):45-51.
  2. Elahi, Mohammed Mehboob.; Jackson, Ian T.; Elahi, Omar et al . Epidemiology of Cleft Lip and Cleft Palate in Pakistan, Plastic & Reconstructive Surgery: May 2004;113(6):1548-1555.
  3. Jamilian, F Nayeri, A Babayan. Incidence of Cleft lip and Palate in Tehran Journal of Indian society of pedodontics and preventive dentistry 2007;25(4):174-176.
  4. BR Rajiv,KV Prasad and et al. The relationship between orofacial clefts and consanguineous marriages: A hospital register-based study in Dharwad,South india., Journal of Cleft Lip Palate and craniofacial Anomalies.2017;4:3-8
  5. Dvivedi J, Dvivedi S. A clinical and demographic profile of the cleft lip and palate in Sub-Himalayan India: A hospital based study. Indian J PlastSurg 2012;45:115-120.
  6. Womersley J, stone DH. Epidemiology of facial clefts. Arch Dis Child.1987;717-720.
  7. Saxen I. Cleft lip and palate in Finland. parental histories, course of pregnancy and selected environmental factors. Int. J Epidemiology.1974;3:263-270.
  8. Shaw GM, Croen LA, Curry CJ. Isolated oral cleft malformations: associations with maternal and infant characteristics in a California population.Teratology.1991;43:225-228.
  9. Viera AR, Orioli IM, Murray JC. Maternal age and oral clefts : A reappraisal. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94: 530-535.
  10. Baird PA, Sadovnick AD, Yee IM. Maternal age and birth defects: A population study.1991;337:527-530.
  11. Camilla Bille, Axel Skytthe and et al, CLEFT LIP AND PALATE. Epidemiology, 2005May; 16(3); 311-316.
  12. Geethpriya and T Marie,IADR world congress on Preventive Dentistry, 2017
  13. Reddy SG, Reddy RR, Sailer HF, Berge SJ. Incidence of cleft lip and palate in the state Andhra Pradesh, South India. Indian J PlastSurg 2010;43(2):184-189.
  14. Ravichandran K, et al. Consanguinity and occurrence of cleft Lip/Palate, A hospital based- registry study in Riyadh. American Journal of Medical Genetics Part A., 2012;158A(3):541-546.
  15. Harville EW, Wilcox AG, Lie RT, Vindenes H, Abyholm F. Cleft lip and palate versus cleft lip only: Are they distinct defects? Am J Epidemiol 2005;162:448-53.

Cite this article: Dinanath Pujari, Sundip Charmode, HS Kadlimatti. THE STUDY OF CLEFT LIP AND PALATE IN NORTH KARNATAKA REGION. Int J Anat Res 2018;6(4.3):6014-6017. DOI: 10.16965/ijar.2018.396