Type of Article:  Original Research

Volume 6; Issue 1.2 (February 2018)

Page No.: 4933-4938

DOI: https://dx.doi.org/10.16965/ijar.2017.511


Renuca Karam *1, Kalpana Th 2, Damayanti N 3, Saratchandra N 4, Sunilkumar Singh S 5, Tarunkumar G 6.

1 Assistant Professor, Dept. of Anatomy, Jawaharlal Nehru Institute of Medical Sciences, Imphal, India.

2 Associate Professor, Dept. of Anatomy, Jawaharlal Nehru Institute of Medical sciences, Imphal, India.

3 Professor, Dept. of Anatomy,Regional Institute of Medical sciences,Imphal, India.

4 Professor,Dept. of Anatomy,Regional Institute of Mediacal Sciences, Imphal, India.

5 Assistant Professor, Dept. of Surgery,Regional Institute of Medical Sciences, Imphal, India.

6 Demonstrator, Jawaharlal Nehru Institute of Medical Sciences, Imphal, India.

Address for correspondence: Dr Renuca Karam, Assistant Professor, Department of Anatomy, Jawaharlal Nehru Institute of Medical Sciences,(JNIMS),Porompat, Imphal-795005, Manipur, India. Mobile no. (91)8974054027 E-Mail: krenuca@gmail.com


Background: To study the morphogenesis of the prostate gland in human foetuses. ‘Prostates’ is a Greek word which literally means “one who stands before”, protector, guardian. It is important from a clinical point of view as it undergoes benign enlargement from the fifth decade,hence  attracting the attention of males around this age and simultaneously the clinicians.

Materials and Methods: 112 foetuses of different gestational ages ranging from 14 weeks (85 mm) to 40 weeks (440 mm), products of terminated pregnancies under MTP Act of India, 1971 and stillbirths were collected from the Department of Obstetrics and Gynaecology, RIMS, Imphal and utilised for the present study with permission from the Institutional Ethical Committee.

Results and observations: The first time of appearance of the prostate gland to the naked eye till its definitive adult shape is studied. Growth and development at specific age period at different age groups are described.

Conclusion: Increase in vertical and transverse dimensions, assumption of adult shape were noted as the age changes.And at term,it has all the three components of the adult tissues although it is not as mature as in adult.This signifies that the growth of the prostate continues postnatally.

Key words: Prostate gland, human foetuses, morphology and development.


  1. Janqueira LC, Carneiro J. The male reproductive system. In: Basic histology text and atlas. 11th New York: McGraw Hill. Lange Medical Publishing Division; 2005. p. 429-33.
  2. Structure of the prostate gland. Available from-http://www.ana.ed.ac.uk/database/prosbase/proshome.html. Accessed date: 14.09.2010.
  3. Skandalakis JE, Colborn GL, Badalament RA, Scaljon W, Parrott TS, Galloway NTM et al. Male genital system. Skandalakis JE, Weidman TA, Colborn GL. editors. In: Skandalakis Surgical Anatomy. 1st Greece: Paschalidis Medical Publications Ltd; 2004. p. 1415-38.
  4. Standring S. Prostate. Ellis H, Healy JC, Johnson D, Williams A. editors. In: Gray’s Anatomy: The anatomical basis of clinical practice. 39th London: Churchill Livingstone; 2005. p. 1301-4.
  5. Hayward SW, Cunha GR. The prostate: development and physiology. 2000; 38(1):1-14.
  6. Larsen WJ. Development of the urogenital system. In: Human embryology. 3rd Philadelphia: Churchill Livingstone; 2001. p. 282-3.
  7. Moore KL, Persaud TVN. The urogenital system. In: The developing human, clinically oriented embryology. 8th Philadelphia: Elsevier; 2008. p. 263-70.
  8. Radmayer C, Lunacek A, Schwentner C, Oswald J, Klocker H, Bartsch G. 5 alpha reductase and the development of the human prostate. Indian J Urol. 2008; 24(3):309-12.
  9. Wein AJ. Normal development of the urogenital system. Kavoussi LR, Novide AC, Partin AW, Peters CA. editors. In pediatric urology. Vol 4. 9th Philadelphia: Saunders Elsevier; 2007. p. 3137-9.
  10. Sahana SN. Genital System In: Human Anatomy. 3rd India: Books and Allied Private Limited; 1980. p. 402-5.
  11. Hammerich KH, Ayala GE, Wheeler TM. Anatomy of the prostate gland and surgical pathology of prostate cancer. In: Hedvig Hricak, Scardino PT, editors. Prostate Cancer. New York: Cambridge University Press; 2009.
  12. Franks LM. Benign nodular hyperplasia of the prostate: a review. Ann Roy Coll Surg Engl. 1953; 14(2): 92-106.

Cite this article: Renuca Karam, Kalpana Th, Damayanti N, Saratchandra N, Sunilkumar Singh S, Tarunkumar G. MORPHOGENESIS OF THE PROSTATE GLAND IN HUMAN FOETUSES. Int J Anat Res 2018;6(1.2):4933-4938. DOI: 10.16965/ijar.2017.511