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IJAR.2020.188

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Type of Article:  Original Research

Volume 8; Issue 3.2 (August 2020)

Page No.: 7680-7691

DOI: https://dx.doi.org/10.16965/ijar.2020.188

MORPHOLOGICAL STUDY OF KIDNEY IN CADAVERS OF WESTERN MAHARASHTRA REGION

Shweta B Shambharkar *1, Shabana Borate 2, Amandeep Kaur Ratta 3, Suresh Gangane 4.

*1 Assistant Professor, Department of Anatomy, Govt. Medical College, Gondia, Maharashtra, India.

2 Associate Professor, Department of Anatomy, Grant Govt. Medical College, Mumbai, Maharashtra, India.

3 National Program Officer, Maternal Health, Norway India Partnership Initiative, IPE Global, New Delhi, India.

4 Ex Professor and Head, Dept of Anatomy, Grant Govt. Medical College, Mumbai, Professor and Head, Terna medical College, New Mumbai, Maharashtra, India.

Corresponding Author: Dr.Shweta B Shambharkar, Plot No.43/B, Dhadiwal Layout, Suyog Nagar Square, Post: Parwati Nagar, Nagpur, Maharashtra-440027, India. Phone: 9960810368 E-Mail: shambharkar.shweta4@gmail.com

ABSTRACT

The Kidneys are the most important organs responsible for removing excess water, salts and waste products from the blood and for maintenance of blood pH. Dimensions of kidney vary in a large interval from birth to adulthood. Changes in kidney length, parenchymal width (PW), cortex width (CW) or volume can be associated with atherosclerotic renal diseases, arterial hypertension, atherosclerotic renovascular disease, or diabetes mellitus or to be indicative of these. The renal dimensions can also be an indicator for unilateral glomerular filtration rate. The coronal section study of kidney provides good knowledge in cases of chronic renal diseases and renal transplantation. The purpose of this study was to determine the anatomical parameters of the kidney in adults. Weight, length, breadth, maximum anteroposterior thickness, cortical width, parenchymal widths were studied in 100 adult cadaveric kidneys. The data was statistically analysed. No statistical significance was seen with respect to the difference in right and left side. But the differences which are frequently seen i.e. length of left kidney greater than the right was also found in the present study, resulting in greater breadth and thickness on the right side. Males had slightly higher values than females, though not statistically significant. The mean values provided in the study could be of use to surgeons, radiologists and nephrologists.

Key words: Morphology, Kidney, Parenchymal, Cortical, Renal Transplantation.

REFERENCES

  1. Healy JC. Urogenital system in Standring S, editor. Gray’s anatomy 40th ed. The Anatomical Basis of Clinical Practice. London: Churchil Livingstone Elsevier; 2008; 1225-1313.
  2. Murlimanju BV, Buraje MK, Kumar N, Prashanth KU, Rao CP, Guru A et al. Morphometric parameters of the human adult kidney: An anatomical study. Int. J. Morphol. 2014; 32(2): 656-9. https://doi.org/10.4067/S0717-95022014000200045
  3. Surcel C, Mirvald C, Gingu C, Udrea A, Savu C, Sinescu I. Morphological aspects of the kidney: Can normality be predicted? Rom J Morphol Embryol.2011;52(4):1325-30. http://www.ncbi.nlm.nih.gov/pubmed/22203941.
  4. Mounier-Vehier C, Lions C, Devos P, Jaboureck O, Willoteaux S, Carre A et al. Cortical thickness: an early morphological marker of atherosclerotic renal disease. Kidney Int. 2002;61(2):591-8. https://doi.org/10.1046/j.1523-1755.2002.00167.x PMid:11849401
  5. Khatun H, Sultana Z, Nur-A-Farhana Islam, Kibria GM , Tawfiq- E-Elahi Chy. Morphological Study of the Kidney in Relation to Age. Bangladesh J. Anat. 2009;7(1) :19-21. https://doi.org/10.3329/bja.v7i1.3012
  6. Mandal S, Mandal P, Basu R. Bilateral Accessory Renal Arteries, Additional Right Renal Vein and Retroaortic Left Renal Vein- A Case Report. Int J Health Sci Res. 2013;3(2):88-93.
  7. Benny Holmberg Umeå University Medical Dissertations New series No 1574 – ISSN 0346-6612 – ISBN 978-91-7459-554-3, 2013.
  8. Naveen kumar S,Seema M,Atoofa J,Sireesha JV .A study of accessory renal arteries and their incidence.Indo American Journal of Pharm Research.2014:4(02).
  9. Gava AL , Freitas FPS , Meyrelles SS, Silva IV and Graceli JB. Gender-dependent effects of aging on the kidney. Braz J Med Biol Res 2011;44(9):905-913. https://doi.org/10.1590/S0100-879X2011007500101 PMid:21956533
  10. Simon AL. Normal Renal Size: An Absolute Criterion. Am J Roentgenol Radium Ther Nucl Med. 1964; 92:270-2.
  11. Kadioglu A. Renal measurements, including length, parenchymal thickness, and medullary pyramid thickness, in healthy children: what are the normative ultrasound values? AJR Am J Roentgenol. 2010 ;194(2):509-15. https://doi.org/10.2214/AJR.09.2986 PMid:20093617
  12. de Lucas C, Nocea A, San RJ, Espínola B, Ecija JL, Vázquez Martul M. [Solitary kidney. Study of renal morphology and function in 95 children]. Nefrologia. 2006;26(1):56-63.
  13. Buchholz NP, Abbas F, Biyabani SR, Afzal M, Javed Q, Rizvi I, Talati J. Ultrasonographic renal size in individuals without known renal disease. J Pak Med Assoc. 2000;50(1):12-6.
  14. Sampaio FJ, Mandarim-de-Lacerda CA. [Morphometry of the kidney. Applied study in urology and imaging]. J Urol (Paris). 1989;95(2):77-80.
  15. Okoye IJ, Agwu KK, Eze CU. Relationship between sonographic renal length and renal parenchymal thickness in normal adult southeast Nigerians. West Afr J Med. 2006 ; 25(3):231-4. https://doi.org/10.4314/wajm.v25i3.28284 PMid:17191425
  16. Muthusami P, Ananthakrishnan R, Santosh P. Need for a nomogram of renal sizes in the Indian population- findings from a single centre sonographic study. Indian J Med Res. 2014 May;139(5):686-93.
  17. Currarino G, Winchester P. Position of the kidneys relative to the spine, with emphasis on children. Am J Roentgenol Radium Ther Nucl Med. 1965 Oct;95(2):409-12. https://doi.org/10.2214/ajr.95.2.409 PMid:5832189
  18. Gourtsoyiannis N, Prassopoulos P, Cavouras D, Pantelidis N. The thickness of the renal parenchyma decreases with age: a CT study of 360 patients. AJR Am J Roentgenol. 1990 Sep;155(3):541-4. https://doi.org/10.2214/ajr.155.3.2117353 PMid:2117353
  19. Bax L, van der Graaf Y, Rabelink AJ, Algra A, Beutler JJ, Mali WP; SMART Study Group. Influence of atherosclerosis on age-related changes in renal size and function. Eur J Clin Invest. 2003 Jan;33(1):34-40. https://doi.org/10.1046/j.1365-2362.2003.01091.x PMid:12492450
  20. Glodny B, Unterholzner V, Taferner B, Hofmann KJ, Rehder P, Strasak A, Petersen J. Normal kidney size and its influencing factors – a 64-slice MDCT study of 1.040 asymptomatic patients. BMC Urol. 2009 Dec 23;9:19. https://doi.org/10.1186/1471-2490-9-19 PMid:20030823 PMCid:PMC2813848
  21. Johnson S, Rishi R, Andone A, Khawandi W, Al-Said J, Gletsu-Miller N, Lin E, Baumgarten DA, O’Neill WC. Determinants and functional significance of renal parenchymal volume in adults. Clin J Am Soc Nephrol. 2011 Jan;6(1):70-6. https://doi.org/10.2215/CJN.00030110 PMid:20847095 PMCid:PMC3022251
  22. Wang X, Vrtiska TJ, Avula RT, Walters LR, Chakkera HA, Kremers WK, Lerman LO, Rule AD. Age, kidney function, and risk factors associate differently with cortical and medullary volumes of the kidney. Kidney Int. 2014 Mar;85(3):677-85. https://doi.org/10.1038/ki.2013.359 PMid:24067437 PMCid:PMC3943620
  23. Venkataramulu M, Vinaykumar N, Prasanna LC. Renal vascular morphology and their significance in predicting accessories. Int J Res Med Sci 2014;2:506-9. https://doi.org/10.5455/2320-6012.ijrms20140526
  24. Emamian SA, Nielsen MB, Pedersen JF, Ytte L. Kidney dimensions at sonography: correlation with age, sex, and habitus in 665 adult volunteers. AJR Am J Roentgenol. 1993 Jan;160(1):83-6v. https://doi.org/10.2214/ajr.160.1.8416654 PMid:8416654
  25. Dixit PK, Sahai SB, Rath B, Garg A, Chowdhury V. Norms for renal parenchymal volume in Indian children. Indian Pediatr. 1994 Sep;31(9):1059-64.
  26. Alam MZ. Gross morphological and histological features of kidneys in Bangladeshi people [thesis] 1994: Department of Anatomy, IPGM and R.
  27. Sinnatamby CS. Last’s anatomy regional and applied. 10th ed. Edinburg: Churchill Livingstone 1999:p.267-280.
  28. MacLachlan MSF. The aging kidney. Lancet 1978;11:143-6. https://doi.org/10.1016/S0140-6736(78)91522-2
  29. Basmajian JV, Slonecker CE. Grant’ method of anatomy. 11th ed. Baltimore: William and Wilkins 1989:p.182-187. https://doi.org/10.1016/0003-2697(89)90740-9
  30. Mullick MH. The arterial pattern of human kidney. Journal of Pakistan medical association 1970;XX(3):77-83.
  31. Aitchison F, Page A. Diagnostic imaging of renal artery stenosis. J Hum Hypertens. 1999 Sep;13(9):595-603. https://doi.org/10.1038/sj.jhh.1000871 PMid:10482969
  32. Okoye IJ, Agwu KK, Idigo FU. Normal sonographic renal length in adult southeast Nigerians. Afr J Med Med Sci. 2005 Jun;34(2):129-31.
  33. Oyuela-Carrasco J, Rodríguez-Castellanos F, Kimura E, Delgado-Hernández R, Herrera-Félix JP. [Renal length measured by ultrasound in adult mexican population]. Nefrologia. 2009;29(1):30-4.
  34. Arooj A, Lam J, Wui YJ, Supriyanto E. Comparison of renal size among different ethnicities. Int J Biol Biomed Eng. 2011;5:221-9.
  35. Preston RA, Epstein M. Ischemic renal disease: an emerging cause of chronic renal failure and end-stage renal disease. J Hypertens. 1997 Dec;15(12 Pt 1):1365-77.
    https://doi.org/10.1097/00004872-199715120-00001 PMid:9431840
  36. Meyrier A, Hill GS, Simon P. Ischemic renal diseases: new insights into old entities. Kidney Int. 1998 Jul;54(1):2-13. https://doi.org/10.1046/j.1523-1755.1998.00968.x PMid:9648058
  37. Bijlstra PJ, Postma CT, de Boo T, Thien T. Clinical and biochemical criteria in the detection of renal artery stenosis. J Hypertens. 1996 Aug;14(8):1033. https://doi.org/10.1097/00004872-199608000-00015
  38. Krijnen P, van Jaarsveld BC, Steyerberg EW, Man in ‘t Veld AJ, Schalekamp MA, Habbema JD. A clinical prediction rule for renal artery stenosis. Ann Intern Med. 1998 Nov 1;129(9):705-11.
    https://doi.org/10.7326/0003-4819-129-9-199811010-00005 PMid:9841602
  39. Davidovits M, Eisenstein B, Ziv N, Krause I, Cleper R, Bar-Sever Z. Unilateral duplicated system: comparative length and function of the kidneys. Clin Nucl Med. 2004 Feb;29(2):99-102. https://doi.org/10.1097/01.rlu.0000109331.37224.5f PMid:14734907
  40. Luke PP, McAlister VC, Jevnikar AM, House AA, Muirhead N, Cross J, Hollomby D, Chin JL. Use of a pelvic kidney for living transplantation: case report and review of the literature. Am J Transplant. 2003 Feb;3(2):235-8. https://doi.org/10.1034/j.1600-6143.2003.00046.x PMid:12603220
  41. Edsman G. Angionephrography and suprarenal angiography; a roentgenologic study of the normal kidney, expansive renal and suprarenal lesions and renal aneurysms. Acta Radiol Suppl. 1957;(155):1-141.
  42. Prince MR, Schoenberg SO, Ward JS, Londy FJ, Wakefield TW, Stanley JC. Hemodynamically significant atherosclerotic renal artery stenosis: MR angiographic features. Radiology. 1997 Oct;205(1):128-36. https://doi.org/10.1148/radiology.205.1.9314974 PMid:9314974
  43. Karasch T, Rubin J. Diagnosis of renal artery stenosis and renovascular hypertension. Eur J Ultrasound. 1998 Jul;7 Suppl 3:S27-39. https://doi.org/10.1016/S0929-8266(98)00029-9
  44. Kasiske BL. Relationship between vascular disease and age-associated changes in the human kidney. Kidney Int. 1987 May;31(5):1153-9. https://doi.org/10.1038/ki.1987.122 PMid:3599655
  45. Lerman LO, Schwartz RS, Grande JP, Sheedy PF, Romero JC. Noninvasive evaluation of a novel swine model of renal artery stenosis. J Am Soc Nephrol. 1999 Jul;10(7):1455-65.
  46. Textor SC. Revascularization in atherosclerotic renal artery disease. Kidney Int. 1998 Mar;53(3):799-811. https://doi.org/10.1038/ki.1998.37 PMid:9507232
  47. Goldblatt H, Lynch J, Hanzal RF, Summerville ww. Studies on experimental hypertension : The production of persistent elevation of systolic blood pressure by means of renal ischemia. J Exp Med. 1934 Feb 28;59(3):347-79. https://doi.org/10.1084/jem.59.3.347
    PMid:19870251 PMCid:PMC2132360
  48. Roger SD, Beale AM, Cattell WR, Webb JA. What is the value of measuring renal parenchymal thickness before renal biopsy?Clin Radiol. 1994 Jan;49(1):45-9 https://doi.org/10.1016/S0009-9260(05)82913-7
  49. Gujar SM; Parmar JK. A study of morphological variations in renal artery. International Journal of Biomedical and Advance Research, [S.l.], 2012;3(11):815-817. https://doi.org/10.7439/ijbar.v3i11.824
  50. Gillaspie C., Miller L.I., and Baskin M.; Anomalous renal vessels and their surgical significance, Anat Rec., 1916;11:77. https://doi.org/10.1002/ar.1090110304
  51. Praveen Kumar DR, Janaki CS, Vijayaraghavan V, Usha K, Chandrika T, Ambareesh: Bilateral variations of renal vasculature : a case report. Int J Med Res Health Sci. 2013;2(3): 678-681. https://doi.org/10.5958/j.2319-5886.2.3.054
  52. Dyson M. Urinary system in Williams PL, Bannister LH, Berry MM, Collins P, editors. Gray’s anatomy. 38th ed. Newyork, Edinburgh, London: Churchill Livingston; 1995.
  53. Moore KL, Persuad TVN. The developing human: Clinically oriented embryology. 8th ed. Philadelphia: Saunders Elsevier; 2008. P. 243-56
  54. Hamilton WJ, Boyd and Mossman. Human Embryology. 4th ed. The University of Michigan; Heffer Publication; 1972.p. 383-93.
  55. Sadler TW, editor. Langman’s medical embryology. 9th Ed. Baltimore; Lippincott Williams and Wilkins; 2006.p. 229-38.
  56. Drake RL, Vogyl W, Mitchell AWM. Gray’s Anatomy for Students. 1st ed. London: Churchill Livingstone Elsevier; 2005.p. 314-24.
  57. Eroschenko VP, editor. diFlore’s Atlas of Histology with functional correlations. 11th ed. Maryland, Philadelphia: Wolter Kluwer Health/Lippincott Williams and Wilkins; 2008.p. 355-73.

Cite this article: Shweta B Shambharkar, Shabana Borate, Amandeep Kaur Ratta, Suresh Gangane. MORPHOLOGICAL STUDY OF KIDNEY IN CADAVERS OF WESTERN MAHARASHTRA REGION. Int J Anat Res 2020;8(3.2):7680-7691. DOI: 10.16965/ijar.2020.188