IJAR.2020.167

Type of Article:  Original Research

Volume 8; Issue 4.1 (November 2020)

Page No.: 7753-7760

DOI: https://dx.doi.org/10.16965/ijar.2020.167

A PRELIMINARY ANTHROPOMETRIC STUDY OF THE RELATIONSHIP BETWEEN DERMATOGLYPHICS AND SICKLE CELL ANAEMIA

James Nketsiah 1, Chrissie Stansie Abaidoo *2, Adjei-Antwi Collins 3.

1 Department of Anatomy, School of Medicine and Dentistry- Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

*2 Professor, Department of Anatomy, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

3 Department of Anatomy, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Corresponding Author:  Prof. Chrissie Stansie Abaidoo, Department of Anatomy, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, Tel: +233 208 126 817, E-Mail: knustsmsanat@gmail.com

ABSTRACT

Dermatoglyphics have been utilized as models for the diagnosis of vast genetic conditions due to their relationship with the genetic make-up of an individual.  However, little studies have been conducted worldwide trying to ascertain the relationship between dermatoglyphics and sickle cell anaemia. Therefore, the present study aimed at generating baseline data to elucidate the possible diagnostic value of dermatoglyphics for earlier detection and screening of Sickle Cell Anaemia (SCA) in Ghana.  A total of 400 participants including 200 SCA patients from Komfo Anokye Teaching Hospital and 200 control group (CG) from KNUST were recruited for this study. The palmprints and fingerprints of the participants were taken and the sickling status of the control group was determined. Distribution of the three major fingerprint patterns, PIC patterns, ATD angle and total finger ridge count (TFRC) were determined. Loop dominated in both the SCA and control groups followed by whorl and arch. PIC 300 dominated in the SCA group while PIC 310 dominated in the control group, this was statistically significant. Also, the study recorded 5 unreported PIC’s (PIC 400, PIC 410, PIC 430, PIC 500 and PIC 510) in the Ghanaian population. The SCA group recorded a mean ATD angle of 43.62o while the control group recorded 41.61o, this was statistically significant. The SCA group recorded a mean TFRC of 67.17 while the control group recorded 78.49. The results of the present study have shown that, there is a relationship between dermatoglyphics and SCA and this will serve as a reliable indicator for earlier detection and screening of sickle cell anaemia especially in neonates.

Key words: Dermatoglyphics, sickle cell anaemia, Ghana.

REFERENCES

[1]. World Health Organization. Sickle cell disease in the African region: Current situation and the way forward. Regional office for Africa, 2006;56:1-2.
[2]. Driss, A., Asare, K. O. and Hibbert, J. M. Sickle Cell Disease in the Post Genomic Era: A monogenic Disease with Polygenic Phenotype. Genomics Insights, 209;23-24.
[3]. Wethers, D. L. Sickle cell disease in childhood: Laboratory diagnosis, Pathophysiology and health maintenance. American Family Physician Journal,2000;62(5):1013-1027.
[4]. Pagrut, K. and Chide, P. Screening for the sickle cell gene in Yavatmal District, Maharashtra, India: An approach to a major public health problem. International Journal of Biomedical and Advance Research, 2017;8(2):50-53.
[5]. Piel, F. B., Steinberg, M. H., and Rees, D. C. Sickle Cell Disease. The new England Journal of Medicine, 2017;1561-1573.
https://doi.org/10.1056/NEJMra1510865
PMid:28423290
[6]. Shetty, R. M. and Sarda, R. Dermatoglyphic Patterns in Sickle Cell Anaemia Patients of Chhattisgarh. Indian Journal of Dental Science, 2017;2(4):2-6.
https://doi.org/10.23880/OAJDS-16000141
[7]. Than, M., Myat, K. A., Khadijah, S., Jamaludin, N., Isa, M. N. Dermatoglyphics of Down’s syndrome patients in Malaysia, a comparative study. Journal of Biological and Clinical Anthropology, 1998;56(4):351-365.
https://doi.org/10.1127/anthranz/56/1998/351
[8]. Andani, R. H., Dharati, K., Ojaswini, M., Nagar, S. K., Kanan, U. and Bhaskar, P. Palmar dermatoglyphics in patients of thalassemia major. National Journal of Medical Research, 2012;2(3):287-290.
[9]. Gualdo, E. A topographical study of the differentiation of the dermatoglyphics in the human fetus. Tulane University, 1948. Thesis.
[10]. Oladipo, G. S., Olabiyi, O., Oremosu, A. A., Noronha, C. C., Okanlawon, A. O. and Paul, C. U. Sickle cell anemia in Nigeria: dermatoglyphic analysis of 90 cases. African Journal of Biochemistry Research, 2007;1(4):54-59.
[11]. Offei, E. B., Abledu, J. K., Osabutey, C. K. and Kesse, D. K. Relationship between palmar dermatoglyphics and academic performance. Journal for Medical and Biomedical Science, 2014;3(2):24-31.
https://doi.org/10.4314/jmbs.v3i2.5
[12]. Parker, C. Fingerprint and intelligence. Fingerprint and Identification Magazine, 1971;3(4):16-18.
[13]. Mensvoort, V. M. Fingerprints-the history of fingerprinting and the study of dermatoglyphics, 2015 http://www.handresearch.com/diagnostics/fingerprints history.htm (accessed 2018 February 14 at 14:07GMT).
[14]. Verma, U., Singroha, R. and Malik, P. A Study to Find Correlation Between Dermatoglyphic Patterns and ABO Blood Groups. International Journal of Anatomy and Research, 2015;3(3): 1293-1297.
https://doi.org/10.16965/ijar.2015.214
[15]. Kahn, H. S., Ravindranath, R., Valdez, R. and Narayan, K. V. Fingerprint ridge-Count difference between adjacent fingertips (dR45) predicts upper-Body tissue distribution: evidence for early gestational programming. Journal of Epidemiology, 2001;153: 338-344.
https://doi.org/10.1093/aje/153.4.338
PMid:11207151
[16]. Shetty, R. M. and Sarda, R. Dermatoglyphic Patterns in Sickle Cell Anaemia Patients of Chhattisgarh. Indian Journal of Dental Science, 2017;2(4):2-6.
https://doi.org/10.23880/OAJDS-16000141
[17]. Bharadwaja, A., Saraswat, P.K., Aggarwal, V., Banerji, P. and Bharadwaja, S. Pattern of Finger-Prints in Different ABO Blood Groups. Journal of Indian Academy of Forensic Medicine, 2004;26(1):6-9.
[18]. Ramani, P., Abhilash, P. R., Sherlin, H. J., Anuja, N., Premkumar, P. and Chandrasekar, T. Conventional dermatoglyphics- Revived concept: A review. International Journal of Pharmacology and Biological Science, 2011;2:446-458.
[19]. Karthikeyan, G. A study on dermatoglyphic pattern in women with breast cancer. PHD Thesis-Madras Medical College and Research Institute, 2013;9:315-317.
[20]. Bhat, G. M., Mukhdoomi, M. A., Shah, B. A. and Ittoo, M. S. Molecular dermatoglyphics: in health and disease – a review. International Journal of Research in Medical Sciences, 2014;2:31- 37.
https://doi.org/10.5455/2320-6012.ijrms20140207
[21]. Ekanem, A. U., Abubakar, H. and Dibal, N. I. A Study of Fingerprints in Relation to Gender and Blood Group among Residents of Maiduguri, Nigeria. Journal of Dental and Medical Sciences, 2014;13(8): 18-20.
https://doi.org/10.9790/0853-13831820
[22]. Nagaraj, G., Tangpu, V., Lakshmi, K. S. and Geetha, R. Study on distribution of fingerprint patterns – A novel experiment for school students. International Journal for Life Sciences and Educational Research, 2015;3(2): 25-30.
[23]. Maled, V., Khode, V., Maled, D., Jain, A., Male, S. and Ruikar, K. Pattern of Fingerprints in Different ABO and Rh Blood Groups. Journal of Indian Academy of Forensic Medicine, 2015;37(2):124-126.
https://doi.org/10.5958/0974-0848.2015.00030.5
[24]. Margi, V. D., Tripathi, S. R., Sharma, S., Nirali, J. K., Patel, A. and Roz, H. Co – Relational Scrutiny between Dermatoglyphics and Blood Group Patterns Revisited. International Journal of Trend in Research and Development, 2016;3(1): 2394-9333.
[25]. Lakshmana N, Nayyar AS, Pavani BV, Ratnam M, Upendra G. Revival of dermatoglyphics: Syndromes and disorders, a review. Advanced Human Biology, 2017;7: 2-7.
https://doi.org/10.4103/2321-8568.199528
[26]. Ramesh, M., Geetha, K. K., Sudhakar, G. and Lakshmi, K. V. A dermatoglyphic study on sickle cell anemia patients of north coastal Andhra Pradesh, south India. International Journal of Current Research,2011;3(8): 62-67.
[27]. Igbigbi, P. S. and Msamati, B. C. B. Palmar and digital dermatoglyphics of indigenous black Zimbabweans. Medical Science Monitor. International Medical Journal of Experimental and Clinical Research, 2002;8(11):757-761.
[28]. Harich, N., Esteban, E., Chafik, A. and Moral, P. Dermatologic characterization of berbers from morocco: Qualitative and quantitative digital and palm data. Annals of Human Biology, 2002;29(4):442-456.
https://doi.org/10.1080/03014460110102205
PMid:12160477
[29]. Kusuma, Y. S., Babu, B. V. and Naidu, J. M. Finger ridge correlations among four tribes of Andra Pradesh. Indian College of Anthropology, 2002;26(1): 319-323.
[30]. Oladipo, G. S. and Akanigha, B. E. Dermatoglyphic patterns in andro- genetic alopecia in a South Eastern Nigeria Population. Journal of Experimented and Clinical Anatomy, 2005;4(2):44 – 47.
https://doi.org/10.4314/jeca.v4i2.30931
[31]. Weninger, M., Aue-Hauser, G. and Scheiber, V. Total Finger Ridge-Count and the Polygenic Hypothesis: A Critique. Human Biology. 1976;48(4):713-725.
[32]. Medland, S. E., Loesch, D. Z., Mdzewski, B., Zhu, G., Monrgomery, G. W. and Martin, N. G. Linkage analysis of a model quantitative trait in humans: finger ridge count shows significant multivariate linkage to 5q14.1 PLoS. Genetics, 2007;3:1736-1744.
https://doi.org/10.1371/journal.pgen.0030165
PMid:17907812 PMCid:PMC1994711

Cite this article: James Nketsiah, Chrissie Stansie Abaidoo, Adjei-Antwi Collins. A PRELIMINARY ANTHROPOMETRIC STUDY OF THE RELATIONSHIP BETWEEN DERMATOGLYPHICS AND SICKLE CELL ANAEMIA. Int J Anat Res 2020;8(4.1):7753-7760. DOI: 10.16965/ijar.2020.167