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IJAR.2017.115

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Type of Article:  Original Research

Volume 5; Issue 1 (March 2017)

Page No.: 3591-3598

DOI: https://dx.doi.org/10.16965/ijar.2017.115

MORPHOLOGICAL AND HISTOLOGICAL VARIATIONS OF HUMAN PLACENTA IN HYPERTENSIVE DISORDERS OF PREGNANCY

Siva Sree Ranga. M.K *1, Adaline Thangam. T.F 2, M.C. Vasantha Mallika 3, M.V. Indira 4.

*1Assistant Professor, Anatomy, Dr.SM CSI Medical College, Karakonam, India.

2 Professor, Obstetrics and Gynaecology, Dr.SM CSI Medical College, Karakonam, India.

3 Associate Professor, Community Medicine, Dr.SM CSI Medical College, Karakonam, India.

4 Professor, Anatomy, Dr.SM CSI Medical College, Karakonam, India.

Corresponding Author: Dr. Siva Sree Ranga. M.K., Siva Sree Sadanam, Vellarada, Thiruvananthapuram Dist. Kerala, India. PIN 695 505; Mobile: 9447696069; E-Mail: sivasreeranga@gmail.com

ABSTRACT

Background: Hypertensive disorders of pregnancy form leading cause of maternal as well as  foetal morbidity and mortality. Many  disorders  of  pregnancy are  associated  with  gross pathological  changes  in  placenta, the feto-maternal organ which is vital for maintaining pregnancy and for promoting growth of the fetus.

Materials and Methods: A cross sectional  study was conducted among placentae from thirty pregnant  mothers  with  hypertension and thirty mothers with uncomplicated pregnancy  in the Department of Obstetrics and Gynaecology, Dr.Somervell Memorial CSI Medical College, Karakonam. The gross morphological and histological examination of placentae was done.

Results: The placental weight, diameter and thickness were reduced in the hypertensive group. The hypertensive  placentae showed more incidence of  infarction, retroplacental haematoma and  calcification. Histologically, hypertensive  placentae showed large number of syncytial knots, cytotrophoblastic proliferation, fibrinoid necrosis and villus hyalinization.  New born babies  of hypertensive  group had reduced  birth weight  and low Apgar score.

Conclusion: Hypertensive  disorders of pregnancy   show significant  differences  in various parameters of placental morphology and histology. Hypertensive  disorders of pregnancy  adversely  influence  the     foetal outcome.

Key words:  Placenta, Infarction, Retro placental haematoma, Calcification, foetal outcome.

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Cite this article: Siva Sree Ranga. M.K, Adlaine Thangam. T.F, M.C. Vasantha Mallika, M.V. Indira. MORPHOLOGICAL AND HISTOLOGICAL VARIATIONS OF HUMAN PLACENTA IN HYPERTENSIVE DISORDERS OF PREGNANCY. Int J Anat Res 2017;5(1):3591-3598. DOI: 10.16965/ijar.2017.115