International Journal of Anatomy and Research

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Type of Article: Original Research

Year: 2016 | Volume 4 | Issue 2 | Page No. 2365-2371

Date of Publication: 31-05-2016



A.R. Sreeranjini *1, N. Ashok 2.

*1 Assistant Professor, Department of Veterinary Anatomy, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala- 680 651, India.

2 Professor & University Head, Department of Veterinary Anatomy, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala- 680 651, India.

Address: Sreeranjini. A.R., Assistant Professor, Department of Veterinary Anatomy, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala -680 651, India, Tel: +91 9447820178.


Back ground: Studies about the normal development of pancreas are beneficial in understanding its normal mode of functioning and thereby help to trace the causes of its dysfunction as in diabetes, pancreatitis or the highly fatal pancreatic cancer. The mechanisms involved in normal prenatal development of exocrine pancreas in goats are poorly understood.
Purpose: The present study was conducted with an aim of contributing some useful information in the field of developmental and pancreatic biology.
Methods and Results: For the present study, the goat embryos from second to fifth month of prenatal life, collected from clinics and farms of Kerala Veterinary and Animal Sciences University and those available in the museum of Department of Veterinary Anatomy, College of Veterinary and Animal Sciences, Mannuthy, Kerala, India were utilized. Samples were fixed in 10% neutral buffered formalin and Bouin’s solution and were processed for light microscopic histological studies. Sections of 5-7µ thickness were cut on a rotary microtome, stained using various routine and special techniques and were examined under Leica DM 2000 LED microscope. During second month of prenatal development, the exocrine pancreas comprised ductules of varying size dispersed within the mesenchyme of both pancreatic primordia. As age advanced and the pancreatic primordia fused, the number and size of ductules increased and developed acini at their end. Later the pancreatic parenchyma was divided into lobules containing groups of acini, blood vessels and intralobular ducts. The present study revealed that the duct system of exocrine pancreas developed before the formation of acini and the number of ducts increased mainly by branching.  Acini developed by the third month of development while distinct lobulation could be noticed in the fourth month of development. The arrangement of lobules, duct system and acini in the fifth month of foetal life indicated the development of a well-organized exocrine pancreas in goats in the prenatal life itself.
Potential implications: The results can also be compared to human data for furthering the knowledge of human biology and medicine. 
KEY WORDS: Exocrine pancreas, Goats, Histology, Prenatal development.


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A.R. Sreeranjini, N. Ashok. PRENATAL DEVELOPMENT OF EXOCRINE PANCREAS IN CROSSBRED GOATS: A HISTOLOGICAL STUDY. Int J Anat Res 2016;4(2):2365-2371. DOI: 10.16965/ijar.2016.221




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