Type of Article : Original Research
Year: 2015 | Volume 3 | Issue 2 | Page No. 1179-1190
Date of Publication: 30-06-2015
STUDY OF THE TOXIC EFFECTS OF FORMALDEHYDE VAPOURS WITHIN THE DISSECTION HALL ON THE FIRST YEAR INDIAN MEDICAL STUDENTS
Surajit Kundu * 1, Pooja Gangrade 2.
*1Assistant Professor, 2 Professor and HOD. Department of Anatomy.
Govt. Medical College, Raigarh. (CG State)-496001. India.
Address: Dr Surajit Kundu, Assistant Professor, Department of Anatomy. Govt. Medical College, Raigarh (CG State) Pin: 496001. India. Ph: +918827264640.
Introduction: Formaldehyde has been used since decades as a time tested embalming fluid material either alone or in mixture with methyl alcohol, thymol crystals, glycerin and water. We in Medical College, Raigarh use 37% formaldehyde, 7% methyl alcohol and the remaining water to prepare embalming solution for cadavers. The concentration of formaldehyde is usually expressed in terms of parts per million (1 ppm= 1.248 mg/cu.m.). Vapours emanating out of the cadavers within the dissection hall is a potential source of health hazard for all medical professionals, student, faculty or technicians. The discomfort includes irritation to the mucous membrane of the nose, respiratory tract, eyes and also causes allergic reaction of the skin.
Materials and Methods: Keeping track of the unconsciously caused complaints, we made a sincere attempt to chalk out the effects of formaldehyde fumes on 100 first MBBS students of Medical College, Raigarh (C.G) as they are virgin in terms of formalin exposure.
Results: The obtained results were quite dramatic. Maximum number of students was positive as among the various symptoms described.
Discussion: Medical students during their dissection course are exposed to formaldehyde, whose exposure is recently considered to be one of the causes of multiple chemical sensitivity. The present study broadly reflects the toxic effects over the first MBBS Indian medical students
Conclusion: The presentation also recommends possible methods for reduction of formalin exposure so that the medical students can enter the dissection hall without any mental tension of toxicity of formalin vapours.
KEY WORDS: Formaldehyde, Toxicity, MBBS students, Dissection, Questionnaire.
- Dewan S Raja, Bahar Sultana. Potential health hazards for students exposed to formaldehyde in the gross anatomy laboratory. Journal of environmental health. 2012;74(6):36-40.
- Jain SR, Nahar PS, Baig MM. Study of Formalin Toxicity in I MBBS Students. International Journal of Science and Research (IJSR) 2012;1(3):233-235.
- FM Onyije, OG Avwioro. Excruciating Effect of Formaldehyde Exposure to Students in Gross Anatomy Dissection Laboratory. The international journal of occupational and environmental medicine 2012;3(2):92-95.
- Girish V. Patil, Shishirkumar, Thejeshwari, Apoorva D, Javed Sharif, C. Sheshgiri, Sushant N. K. Physical reactions of formalin used as cadaver preservative on first year medical students. Journal of evidence based medicine and health (JEBMH) 2014;5(5):279-283.
- Prashant Patil, Sandip Meghnad Hulke, Avinash Thakare. Effect of formalin on pulmonary function : a nine months longitudinal study. Research Journal of Pharmaceutical, Biological and Chemical Sciences 2012;3(1): 211-216.
- Farah Khalid, Praveen Tripathy. Acute effects of formalin on pulmonary functions in gross anatomy laboratory; Indian journal of physiology pharmacology 2009; 53(1):93-96.
- Yadav Abhijeet, Mukul Yadav. A study of the effects of formalin of first year MBBS students. Scholars journal of applied medical sciences (SJAMS) 2014;2(5B):1588-1590.
- Rashmi neginhal, Anita Herur, Surekharani Chinagudi, G B Rairam, Sanjeev Kolagi, Udaya Ambi. Cardio-respiratory effects of acute exposure to formaldehyde in gross anatomy laboratory in medical students – A comparative study. Medica Innovatica. 2013;2(1):32-35.
- Dr Gaurav Agnihotri, Manideep Gill Sagoo. Reactions of first year Indian medical students to the dissection hall experience. NJIRM 2010;1(4):4-9.
- Determination of Acute Reference Exposure Levels for Air borne Toxicants; acute toxicity summary; Formaldehyde; March 1999.
- Dr Daksha Dixit, Dr P D Athavia, Dr H M Pathak. Toxic effects of embalming fluid on medical students and professionals. JIAFM 2005;27(4):209-211.
- Toxicological profile for formaldehyde U.S. department of health and human services public health service agency for toxic substances and disease registry, July 1999
- Weber-Tschopp A, Fisher T, Granjean E. Irritating effects of formaldehyde on men. Int Occup Environ Health 1977;39:207-218.
- Green DJ, Sauder LR, Kulle TJ, Bascom R. Acute response to 3.0 ppm formaldehyde in exercising healthy nonsmokers and asthmatics. Am Rev Respir Dis 1987;135:1261-1266.
- Feinman SE, editor. Formaldehyde sensitivity and toxicity. Boca Raton (FL): CRC Press Inc; 1988.
- Porter JAH. Acute respiratory distress following formalin inhalation. Lancet 1975;1:603-604.
- Solomons K, Cochrane JWC. Formaldehyde toxicity: Part 1. Occupational exposure and a report of 5 cases. S Afr Med J. 1984;66:101-102.
- Pazdrak K, Gorski P, Krakowiak A, Ruta U. Changes in nasal lavage fluid due to formaldehyde inhalation. Int Arch Occup Environ Health 1993;64(7):515-519.
- Sauder LR, Chatham MD, Green DJ, Kulle TJ. Acute pulmonary response to formaldehyde exposure in healthy nonsmokers. J Occup Med 1986;28(6):420-424.
- Sim VM, Pattle RE. Effect of possible smog irritants on human subjects. J Am Med Assoc. 1957;165:1908-1913.
- Feron VJ, Til HP, de Vrijer F, et al. Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment. Mutat Res. 1991;259:363-385.
- Casanova-Schmitz M, Raymond MD, Heck H d'A;Oxidation of formaldehyde and acetaldehyde by NAD+-dependent dehydrogenases in rat nasal mucosal homogenates. Biochem Pharmacol; 1984b;33:1137-1142.
- Casanova M, Heck Hd'A. The impact of DNA-protein cross-linking studies on quantitative risk assessments of formaldehyde. CIIT Act 1991;11:1-6.
- Loomis TA. 1979. Formaldehyde toxicity. Arch Pathol Lab Med. 1979;103:321-324.
- Casanova M, Heck Hd'A; Further studies of the metabolic incorporation and covalent binding ofinhaled [3H]- and [14C] formaldehyde in Fischer-344 rats: Effects of glutathione depletion. Toxicol Appl. Pharmacol. 1987;89:105-121.
Surajit Kundu, Pooja Gangrade. STUDY OF THE TOXIC EFFECTS OF FORMALDEHYDE VAPOURS WITHIN THE DISSECTION HALL ON THE FIRST YEAR INDIAN MEDICAL STUDENTS. Int J Anat Res 2015;3(2):1179-1190. DOI: 10.16965/ijar.2015.195