International Journal of Anatomy and Research



Welcome to International Journal of Anatomy and Research

b2



b3

 

 

Type of Article : Original Article

Year: 2014 | Volume 2 | Issue 4 | Page No. 806-809

Date of Publication: 31-12-2014

DOI: 10.16965/ijar.2014.553


EFFECTS OF FRUITS OF BARRINGTONIA RACEMOSA LINN. ON HUMAN POLYMORPHONUCLEAR CELL

Sudha Patil 1, Mahesh Ramu Patil 2, Prabhakar Patil *3, Rohit Dixit 4, Rajesh C Sharma 5.

1,*3,4,5 Navodaya Medical College Raichur, Karnataka, India.
2 R.C. Patel College of Pharmacy, Shirpur, Dhule, Maharashtra, India.

Address: Dr. Prabhakar Patil, Navodaya Medical College, Raichur, Karnataka, India. Mobile No. +919900346851.
E-Mail:
drprpatil2006@gmail.com

Abstract

The objective of present study was to investigate Petroleum ether, ethyl acetate and hydroalcoholic extracts of B. racemosa fruits in vitro on human polymorphonuclear (PMN) cells to screen their effects on phagocytosis and chemotaxis. Ethyl acetate extract of B. racemosa fruits was found to be a stimulant of PMN cell phagocytosis of Nitroblue tetrazolium (NBT) dye and candida albicans. It also stimulated intracellur killing capacity of PMN cells. It was further found to increase the chemotaxis of human PMN cells. While, petroleum ether extract and hydroalcoholic extract were lesser active as far as these activities are concerned.
KEYWORDS: Barringtonia racemosa, Phagocytosis, Chemotaxis, Polymorphonuclear cells.

References

  1. N. M. Hussin, R. Muse, S. Ahmad, J. Ramli, M. Mahmood, M. R. Sulaiman, M. Y. A. Shukor, M. F. A. Rahman and K. N. K. Aziz Antifungal activity of extracts and phenolic compounds from Barringtonia racemosa L. (Lecythidaceae) African Journal of Biotechnology 2009;8(12):2835-2842.
  2. Mandana Behbahani, Abdul Manaf Ali, Radzali Muse and Noorjahan Banu Mohd. Anti-oxidant and anti-inflammatory activities of leaves of Barringtonia racemosa. Journal of Medicinal Plants Research 2007;1(5):095-102.  
  3. Khan S, Jabbar A, Hasan CM, Rashid  MA. Antibacterial activity of Barringtonia racemosa.  J   Ethnopharmacol 2001;72:162-164.
  4. Thomas T.J, Panikkar B, Subramoniam A, Nair M, Panikkar K.R. Short   communication, antitumor property and toxicity of Barringtonia racemosa roxb seed extract in mice .J Ethnopharmacol. 2002;82:223-227.
  5. Prabhakar R. Patil , Mahesh R. Patil, , Abhay Mane, Sudha Patil. Immunomodulatory effects of fruits of Barringtonia racemosa Linn. International Journal of Basic & Clinical Pharmacology 2013;2 (2):216-219.
  6. Wilkinson P.C. Neutrophil leukocyte function test. Chapter 13 In: Thomson RA, editor. Techniques in clinical Immunology .Oxford London: Blackwell Scientific Publications 1981a, II nd edition; p. 276-278.
  7. Manosroj A, Saraphanchotiwitthaya A, Manosroj J. Immunomodulatory activities of Clausena excavata Burm.f.wood extracts. J Ethnopharmacol. 2003;89:155-160.
  8. Wilkinson P.C. Neutrophil leukocyte function test. Chapter 13 In: Thomson RA,editor.    Techniques in clinical Immunology. Oxford London: Blackwell Scientific Publications 1981b, II nd edition; p.287-289.
  9. Wilkinson P.C. Neutrophil leukocyte function test Chapter 13 In: Thomson RA,editor.  Techniques in clinical Immunology .Oxford London: Blackwell Scientific Publications 1981c, II nd edition; p. 290-.291.
  10. Wilkinson P.C. Neutrophil leukocyte function test Chapter 13 In: Thomson RA, editor.  Techniques in clinical Immunology. Oxford London: Blackwell Scientific Publications 1981d, II nd edition; p. 279-.283.


Sudha Patil, Mahesh Ramu Patil, Prabhakar Patil, Rohit Dixit, Rajesh C Sharma. EFFECTS OF FRUITS OF BARRINGTONIA RACEMOSA LINN. ON HUMAN POLYMORPHONUCLEAR CELL. Int J Anat Res 2014;2(4):806-809. DOI: 10.16965/ijar.2014.553

b2



b3




Search

Volume 1 (2013)

Volume 2 (2014)

Submit Manuscript