International Journal of Anatomy and Research

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Type of Article : Case Report

Year: 2014 | Volume 2 | Issue 4 | Page No. 689-691

Date of Publication: 30-11-2014

DOI: 10.16965/ijar.2014.526


Sharmila Pal *1, Rupa Biswas 2, Debopriya Danda 3, Jadab Chandra Chattopadhyay 4 , Tarun Kumar Danda 5 .

*1 Professor, Dept. of Anatomy, Medical College, Kolkata, West Bengal, India.
2 Nil Ratan Sircar Medical College, Kolkata, West Bengal, India.
3 A.B.Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.
4 Medical College, Kolkata, West Bengal, India.
5 ICARE Institute of Medical Sciences & Research, Haldia, West Bengal, India.

Address: Prof. Dr. Sharmila Pal, Dept. of Anatomy, Medical College, Kolkata 88, College Street, Kolkata-700073, West Bengal, India.


A neonate with rare congenital anomalies was born at 25 weeks of gestation and died within 17 minutes of birth. On examination of the baby, it was found that the lower limbs were malrotated and fused all along the length with six toes. External genitalia, urogenital and anal orifices were absent. At autopsy, a single umbilical artery was found arising from the abdominal aorta. Both the kidneys were polycystic and were situated in the iliac fossae. Distal portion of the large gut beyond caecum was absent and rectum was atretic. No reproductive organ was found. On the basis of the findings, the case was diagnosed as sirenomelia (mermaid syndrome).
KEY WORDS: Sirenomelia, polycystic kidneys, single umbilical artery.


  1. Carlos GA, Endrika H, Domingo GL, Maria Luisa MF, Federica B, Maria AR. A clinical and experimental overview of sirenomelia: insight into the mechanisms of congenital limb malformations. Dis Model Mech 2011;4(3):289-299.
  2. Schiesser M, Holzgreve W, Lapaire O, Willi N, Lüthi H, Lopez R, Tercanli S. Sirenomelia, the mermaid syndrome- detection in the first trimester. Prenat Diag 2003;23:493-5.
  3. Van Keirsbilck J, Cannie M, Robrechts C, de Ravel T, Dymarkowski S, Van den Bosch T, Van Schoubroeck D. First trimester diagnosis of Sirenomelia. Prenat Diagn2006;26:684-8.
  4. Sikandar R, Munim S. Sirenomelia, the Mermaid Syndrome: case report and a brief review of literature. J Pak Med Assoc 2009;59(10):721-3.
  5. 5.Reddy KR, Srinivas S , Kumar S, Reddy S, Hariprasad, Irfan GM. Sirenomelia  A Rare Presentation. Journal of Neonatal Surgery2012;1(1):7.
  6. Baxi L, Warren W, Collins MH, Timor-Tritsch IE. Early detection of caudal regression syndrome with transvaginal scanning. Gynecol 1990;75:486-90.
  7. Padmanabhan R. Retinoic acid –induced caudal regression syndrome in the mouse fetus. Reprod Toxicol 1998;12:139-51.
  8. Sarpogs S, Headings V : Sirenomelia accompanying exposure of the embryo to cocaine. South Med J 1992;85:545-7.
  9. Sirtori M, Ghidini A, Romero R, Hobbins JC. Prenatal diagnosis of sirenomelia. J Ultrasound Med 1989;8:83-88.
  10. Baktar O, Benvischke K, Masliah E. Sirenomelia of an intracytoplasmic sperm injection conception: a case report and review of mechanism. Pediatr Dev Pathol 2006;9:245-53.

Sharmila Pal, Rupa Biswas, Debopriya Danda, Jadab Chandra Chattopadhyay, Tarun Kumar Danda. SIRENOMELIA: MERMAID SYNDROME. Int J Anat Res 2014;2(4):689-691. DOI: 10.16965/ijar.2014.526




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