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IJPR.2019.102

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Type of Article:  Original Research

Volume 7; Issue 2 (March 2019)

Page No.: 3011-3015

DOI: https://dx.doi.org/10.16965/ijpr.2019.102

NEUROPHYSIOLOGICAL CHANGES IN PERSON WITH INSULIN DEPENDENT AND NON INSULIN DEPENDENT DIABETES MELLITUS

Maitrey Pandya *1, Miral Damani 2.

*1,2  MPT, Lecturer, Kamdar institute of physiotherapy, Rajkot,Gujrat, India.

Address for Correspondence: Dr. Maitrey Pandya, MPT, Lecturer, Kamdar institute of physiotherapy, Rajkot,Gujrat, India. E-Mail: maitreypandya07@gmail.com

ABSTRACT

Background: Diabetes mellitus is a disease caused by an inability of the body to metabolize glucose properly. The prevalence of diabetes is rapidly rising all over the globe at an alarming rate. As Insulin and non-insulin dependent diabetes shows their effect on various physiological systems includes central, peripheral and autonomic nervous systems, musculoskeletal, cardiovascular and other vital systems. A common complications due to the IDDM and NIDDM includes peripheral neuropathy, retinopathy, nephropathy and vascular complication. Insulin and non-insulin dependent diabetes mellitus, both affect the peripheral nervous system significantly. Therefore we would like to find out neurophysiological changes on peripheral nervous systems between insulin and non-insulin dependent diabetes mellitus.

Aim: To find out the Neuro-physiological changes between IDDM and NIDDM.

Materials and Method: 120 individuals screened with SF36 (general health good and above) were included with age limit between 25 to 60 years. Those individuals having a history of hospitalization in last 1 year, acute fever, present history of radiculopathy and open wound were excluded. They were divided into 2 groups IDDM and NIDDM. For nerve conduction study–distal latency, amplitude and NCV of sensory and motor nerves were performed. Nerve conduction studies of common peroneal, tibial and sural nerves were examined in both groups. Latency, NCV and CMAP/SNAP were taken as outcome measures. Result and Discussion: Bio-statistical analysis has been done using Mann-Whitney test. Result suggest that there is a significant difference in Neurophysiological changes (p<0.05) between IDDM and NIDDM groups. Conclusion: In context to our study and neurophysiological findings, individuals with IDDM must be taken into consideration for promotion, prevention, and care as compared to NIDDM for secondary complications.

Key words: Insulin dependent diabetes mellitus (IDDM), Non-insulin dependent diabetes mellitus (NIDDM), Neurophysiological changes.

REFERENCES

  1. AL Kakrani, Gokhale, Karan Vohra et al. Clinical and Nerve Conduction Study Correlation in Patients of Diabetic Neuropathy. Journal of the association of physicians of India. .2014; 62: 24-7.
  2. Sarah Wild, Gojka, Anders et al. Global Prevalence of Diabetes-Estimates for the year 2000 and projections for 2030. The American diabetes association. 2004; 27: 1047-53.
  3. Lindsay, Bone, Callander. Neurology and neurosurgery illustrated. 3rd 1997:525.
  4. Aspi and Sharukh Golwala. Medicine for students. 22nd 2009; 437-44.
  5. Mamta , Abigail, Catherine et al. Peripheral Neuropathy in Adolescents and Young Adults With Type1 and Type2 Diabetes From the search for Diabetes in Youth Follow-up Cohort. American diabetes association. 2013; 36:3903-9.
  6. Jie Ding, Carol, Kamran et al. Early Retinal Arteriolar Changes and Peripheral Neuropathy in Diabetes. The American Diabetes Association. 2012; 35:1098-1104.
  7. Callaghan, Little, Feldman et al. Enhanced glucose control for preventing and treating diabetic neuropathy (Review). The cohort collaboration.2012; 6:1-55.
  8. Jun Kimura M. D. Electro diagnosis in Diseases of Nerve and Muscle. Principles and Practice. 3rd; 1987: 653.
  9. Claus, Mustafa, Vogel et al. Assessment of diabetic neuropathy. Definition of norm and discrimination of abnormal nerve function. Muscle nerve 1993; 16:757–768.
  10. Dyck, Karnes, Daube et al. Clinical and Neuro pathological criteria for the diagnosis and staging of diabetic polyneuropathy. Brain. 1985; 108:861–880.
  11. Properties of cutaneous afferents in diabetic neuropathy. Brain. 1989; 112:1359–1376.
  12. Niakan, Harati. Sympathetic skin response in diabetic peripheral neuropathy. Muscle nerve. 1988;11:261–264.
  13. Le Quesne, Fowler, Parkhouse . Peripheral neuropathy profile in various groups of diabetics. Journal of neurology neurosurgery and psychiatry. 1990; 53:558–563.
  14. Halar, Graf, Halter et al. Diabetic neuropathy, A clinical, laboratory and electro diagnostic study. Archives of physical medicine and rehabilitation. 1982; 63:298–303.
  15. Conrad B, Aschoff JC, Fischler M.neurophysiological changes in patients with long duration diabetes.J Neurology. 1975;210:151–159.
  16. Arindam, Santa, Premchandra. Prevalence of peripheral neuropathy in newly diagnosed type 2 diabetics. International Journal of diabetes devloping country. 2005;25:30-3.
  17. Kari,Mortin, Bassam et al. Small and large fiber neuropathy after 40 years of type 1 diabetes. Diabetes Care.2013; 36:3712-17.
  18. Fagius, Jameso. Effects of aldose reductase inhibitor treatment in diabetic polyneuropathy. Journal of neurology neurosurgery and psychiatry.1981; 44:991–1001.
  19. Ram, Sadeh, Walden et al. Vascular insufficiency quantitatively aggravates diabetic neuropathy. Archives of neurology. 1991;48:1239–1242.
  20. Sladky, Tschoepe, Greenberg et al. Peripheral neuropathy after chronic endoneurial ischemia. Annals of neurology. 1991; 29:272–278.
  21. Malik, Veves, Masson et al. Endoneurial capillary abnormalities in mild human diabetic neuropathy. Journal of neurology neurosurgery and psychiatry. 1992;55:557–561.
  22. Vinik, Holland, Beua et al. Diabetic neuropathies. Diabetes care 1992;15 (12): 1926-1951.
  23. Gregersen.Diabetic neuropathy, influence of age, sex, metabolic control and duration of diabetes on motor conduction velocity. Neurology 1967; 17: 972-980.
  24. Valensi, Giroux, Seeboth et al. Diabetic peripheral neuropathy: effects of age, duration of diabetes, glycemic control and vascular factors. Journal of Diabetes and its Complication. 1997; 11: 27-34.
  25. Kuniman, Wilborn, Mc Cann, et al. Prevalence of diabetic complications in relation to risk factors. Diabetes 1986; 35: 1332-1339.

Cite this article: Maitrey Pandya, Miral Damani. NEUROPHYSIOLOGICAL CHANGES IN PERSON WITH INSULIN DEPENDENT AND NON INSULIN DEPENDENT DIABETES MELLITUS. Int J Physiother Res 2019;7(2):3011-3015. DOI: 10.16965/ijpr.2019.102
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