{"id":441,"date":"2017-03-30T16:26:17","date_gmt":"2017-03-30T16:26:17","guid":{"rendered":"http:\/\/www.ijmhr.org\/IntJAnatRes\/?page_id=441"},"modified":"2017-04-01T01:36:30","modified_gmt":"2017-04-01T01:36:30","slug":"ijar-2017-115","status":"publish","type":"page","link":"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2017-115\/","title":{"rendered":"IJAR.2017.115"},"content":{"rendered":"
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Type of Article:<\/strong>\u00a0 Original Research<\/h3>\n

Volume 5; Issue 1 (March\u00a02017)<\/strong><\/h3>\n

Page No.:<\/strong> 3591-3598<\/h3>\n

DOI:\u00a0<\/strong>https:\/\/dx.doi.org\/10.16965\/ijar.2017.115<\/h3>\n

MORPHOLOGICAL AND HISTOLOGICAL VARIATIONS OF HUMAN PLACENTA IN HYPERTENSIVE DISORDERS OF PREGNANCY<\/h3>\n

Siva Sree Ranga. M.K *1<\/sup>, Adaline Thangam. T.F 2<\/sup>, M.C. Vasantha Mallika 3<\/sup>, M.V. Indira 4<\/sup>.<\/strong><\/p>\n

*1<\/sup>Assistant Professor, Anatomy, Dr.SM CSI Medical College, Karakonam, India.<\/p>\n

2<\/sup> Professor, Obstetrics and Gynaecology, Dr.SM CSI Medical College, Karakonam, India.<\/p>\n

3<\/sup> Associate Professor, Community Medicine, Dr.SM CSI Medical College, Karakonam, India.<\/p>\n

4<\/sup> Professor, Anatomy, Dr.SM CSI Medical College, Karakonam, India.<\/p>\n

Corresponding Author<\/strong>: Dr. Siva Sree Ranga. M.K., Siva Sree Sadanam, Vellarada, Thiruvananthapuram Dist. Kerala, India. PIN 695 505; Mobile: 9447696069;\u00a0E-Mail:<\/strong> sivasreeranga@gmail.com<\/p>\n

ABSTRACT<\/strong><\/p>\n

Background: <\/strong>Hypertensive disorders of pregnancy form leading cause of maternal as well as\u00a0 foetal morbidity and mortality. Many\u00a0 disorders\u00a0 of\u00a0 pregnancy are\u00a0 associated\u00a0 with\u00a0 gross pathological\u00a0 changes\u00a0 in\u00a0 placenta, the feto-maternal organ which is vital for maintaining pregnancy and for promoting growth of the fetus.<\/p>\n

Materials and Methods: <\/strong>A cross sectional\u00a0 study was conducted among placentae from thirty pregnant\u00a0 mothers\u00a0 with\u00a0 hypertension and thirty mothers with uncomplicated pregnancy\u00a0 in the Department of Obstetrics and Gynaecology, Dr.Somervell Memorial CSI Medical College, Karakonam. The gross morphological and histological examination of placentae was done.<\/p>\n

Results:<\/strong> The placental weight, diameter and thickness were reduced in the hypertensive group. The hypertensive\u00a0 placentae showed more incidence of\u00a0 infarction, retroplacental haematoma and\u00a0 calcification. Histologically, hypertensive\u00a0 placentae showed large number of syncytial knots, cytotrophoblastic proliferation, fibrinoid necrosis and villus hyalinization.\u00a0 New born babies\u00a0 of hypertensive\u00a0 group had reduced\u00a0 birth weight\u00a0 and low Apgar score.<\/p>\n

Conclusion: <\/strong>Hypertensive\u00a0 disorders of pregnancy\u00a0\u00a0 show significant\u00a0 differences\u00a0 in various parameters of placental morphology and histology. Hypertensive\u00a0 disorders of pregnancy\u00a0 adversely\u00a0 influence\u00a0 the\u00a0\u00a0\u00a0\u00a0 foetal outcome.<\/p>\n

Key words:<\/strong>\u00a0 Placenta, Infarction, Retro placental haematoma, Calcification, foetal outcome.<\/p>\n

REFERENCES<\/strong><\/p>\n

    \n
  1. A, Jain.M.L. Morphological Study of Placenta in Pregnancy Induced Hypertension with its Clinical Relevance.J.Anat.Soc.India,2001;50:24-27.<\/li>\n
  2. Park K. Textbook of Preventive and SocialMedicine, 20th edn, BanarsidasBhanot Publishers, Jabalpur: Pg 482,2009.<\/li>\n
  3. Tangirala S, kumari D. Placental morphology in hypertensive disorders and its correlation to neonatal outcome. IAIM, 2015;2(11):35-38.<\/li>\n
  4. EskildA,Vatten LJ. Do pregnancies with PE have smallplacentas? A population study of 317688 pregnancieswith & without growth restriction in the offspring.BJOG. 2010; 117:1521-1526.<\/li>\n
  5. A, Bhagwat SS,, Mehta CD, Relation between placental surface area, infarction and foetal distress in pregnancy induced hypertension with its clinical relevance. J AnatSocInd 2004;53;1:27-30.<\/li>\n
  6. MajumdarS,Dasgupta H. A Study of Placenta In Normal And Hypertensive Pregnancies. . J AnatSocInd 2005;54:1-9.<\/li>\n
  7. Rosana RM Correa, Daniel B. Gilio, Camila L. Cavellani, Marina C. Paschoini, Fl\u00e1via A. Oliveira, Lu\u00eds C. Peres, Marlene A. Reis, Vicente P. A. Teixeira and Eumenia C. C. Castro Placental morphometrical and histopathology changes in the different clinical presentations of Hypertensive Syndromes in Pregnancy. Arch Gynecolobstr 2008;277(1):201-206.<\/li>\n
  8. Kurdukar MD, Deshpande NM. Placenta in Pregnancy induced Hypertension. Indian J PatholMycrobiol 2007;50:493-497.<\/li>\n
  9. Abdul HafeezBaloch, Salma FarrukhMemon, Asmat Kamal Ansari.Comparison of Placentae from Hypertension Associated Pregnancies and Normal Pregnancies .JLUMHS January-April 2012;11(01).<\/li>\n
  10. Duley L. Preeclampsia and hypertensive disorders of pregnancy. Br Medl Bull 2003;67:161-176.<\/li>\n
  11. Fact and Fancy.ArchPathol Lab Med. 1991;115:672-679.<\/li>\n
  12. Kotgirwar \u00a0Sheetal, Mohd \u00a0Imtiaz, Gupta \u00a0Vanita, Trivedi \u00a0SoumitMorphology of placenta in pregnancy induced hypertension and its foetal outcome .Journal of Advance Researches in Biological Sciences,2009;1(2):109-114.<\/li>\n
  13. Virupaxi RD, Potturi BR, Shirol VS, Desai SP, Hukkeri VB. Morphology of placenta and its relation with small for date babies in 950 live births. Rec Res SciTechnol 2011;3:123-6.<\/li>\n
  14. David J.P. Barker, Kent L. Thornburg, Clive Osmond, EeroKajantie ,Johan G. Eriksson.The surface area of the placenta and hypertensioninth e offspring in later life.Int. J. Dev. Biol. 2010;54:525-530.<\/li>\n
  15. AbhilashaDadhich ,SushmaK.Kataria, Kushal R. Kataria, PushpaPotaliya. Study of effect of eclampsia and chronic hypertension on gross morphology of placenta. <\/strong>Int J Biol Med Res. 2012;3(2):1771-1773.<\/li>\n
  16. Pradeep S Londhe, Abhay B Mane. Morphometric study of placenta and its correlation in normal and hypertensive pregnancies. International Journal of Pharma and Bio Sciences:Oct-Dec 2011;2(4):975-6299.<\/li>\n
  17. Johan Eriksson, Tom Forsen, JaakoTuomilehto, Clive Osmond, David Barker. Fetal &Chid hood growth andhypertension in adult life. Hypertension. 2000;36:790-794.<\/li>\n
  18. Pandure M.M.,Ghosh D.K morphology of preterm placenta and it\u2019s clinicopathological corelation Pravara Med Rev 2011;6(2).<\/li>\n
  19. AparnaNarasimha, Vasudeva DS. Spectrum of changes in placenta in toxaemia of pregnancy. Indian Journal of Pathology and Microbiology March 2011;54(1):15-20.<\/li>\n
  20. Maimoona Ahmed, Rekha G. Daver. Study of placental changes in pregnancy induced hypertension Int J Reprod Contracept Obstet Gynecol. 2013 Dec;2(4):524-527.<\/li>\n
  21. Deepalaxmi Salmani et al. Study of structural changes in placenta in pregnancy-induced hypertension, \u00a0Nat SciBiol Med. 2014 ;5(2): 352\u2013355.<\/li>\n<\/ol>\n

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    \n \t Cite this article:<\/strong><\/span> Siva Sree Ranga. M.K, Adlaine Thangam. T.F, M.C. Vasantha Mallika, M.V. Indira. MORPHOLOGICAL AND HISTOLOGICAL VARIATIONS OF HUMAN PLACENTA IN HYPERTENSIVE DISORDERS OF PREGNANCY. Int J Anat Res 2017;5(1):3591-3598. DOI:\u00a0<\/strong>10.16965\/ijar.2017.115 \u00a0\n <\/div>\t\n\t\t\n","protected":false},"excerpt":{"rendered":"

    Type of Article:\u00a0 Original Research Volume 5; Issue 1 (March\u00a02017) Page No.: 3591-3598 DOI:\u00a0https:\/\/dx.doi.org\/10.16965\/ijar.2017.115 MORPHOLOGICAL AND HISTOLOGICAL VARIATIONS OF HUMAN PLACENTA IN HYPERTENSIVE DISORDERS OF PREGNANCY Siva Sree Ranga. M.K *1, Adaline Thangam. T.F 2, M.C. Vasantha Mallika 3, M.V. Indira 4. *1Assistant Professor, Anatomy, Dr.SM CSI Medical College, Karakonam, India. 2 Professor, Obstetrics and
    + Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-441","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/comments?post=441"}],"version-history":[{"count":2,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/441\/revisions"}],"predecessor-version":[{"id":476,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/441\/revisions\/476"}],"wp:attachment":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/media?parent=441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}