{"id":3090,"date":"2025-09-04T01:16:50","date_gmt":"2025-09-04T01:16:50","guid":{"rendered":"https:\/\/www.ijmhr.org\/IntJAnatRes\/?page_id=3090"},"modified":"2025-09-04T01:16:50","modified_gmt":"2025-09-04T01:16:50","slug":"ijar-2025-227","status":"publish","type":"page","link":"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2025-227","title":{"rendered":"IJAR.2025.227"},"content":{"rendered":"
<\/i> DOWNLOAD PDF<\/span><\/a><\/div><\/div><\/div>
<\/i> Table of Contents<\/span><\/a><\/div><\/div><\/div><\/div>\n

Type of Article:<\/strong> \u00a0Original Research<\/h3>\n

Volume 13; Issue 3 (September 2025)<\/strong><\/h3>\n

Page No.:<\/strong> 9332-9338<\/h3>\n

DOI:\u00a0<\/strong>https:\/\/dx.doi.org\/10.16965\/ijar.2025.227<\/h3>\n

Study of Histogenesis of Human Fetal Renal Medulla by Using Masson\u2019s Trichrome and PAS Stains<\/h3>\n

Rahul Kisan Ukey 1<\/sup>, Dharam Singh Rathia *2<\/sup>, Tarkeshwar Devidas Golghate 3<\/sup>, Amit Purushottam Tirpude 4<\/sup>, Soumitra Trivedi 5<\/sup>.<\/strong><\/p>\n

1<\/sup> Assistant Professor, Department of Anatomy, AIIMS, Raipur, C.G.\u00a0University \u2013 AIIMS, Raipur, Chhattisgarh, India. ORCiD:\u00a0<\/strong>https:\/\/orcid.org\/0000-0002-7775-5132\u00a0\u00a0\u00a0<\/p>\n

*2<\/sup> Assistant Professor, Department of Anatomy, AIIMS, Raipur, C.G.\u00a0University \u2013 AIIMS, Raipur, Chhattisgarh, India. ORCiD:\u00a0<\/strong>https:\/\/orcid.org\/0000-0001-7141-1171<\/p>\n

3<\/sup> Professor and Head of Department, Department of Anatomy, Government Medical College, Bhandara, M.S. University, Maharashtra University of Health Sciences, Nashik, Bhandara, Maharashtra, India. ORCiD:<\/strong>\u00a0https:\/\/orcid.org\/0009-0005-9867-2570<\/p>\n

4<\/sup> Additional Professor, Department of Anatomy, AIIMS, Raipur, C.G.\u00a0University \u2013 AIIMS, Raipur, Chhattisgarh, India. ORCiD:\u00a0<\/strong>https:\/\/orcid.org\/0000-0003-0223-2270<\/p>\n

5<\/sup> Professor & Head, Department of Anatomy, AIIMS, Raipur, C.G.\u00a0University \u2013 AIIMS, Raipur, Chhattisgarh, India. ORCiD:\u00a0<\/strong>https:\/\/orcid.org\/0000-0003-0379-2173<\/p>\n

Corresponding Author: <\/strong>Dr. Dharam Singh Rathia, Assistant Professor, Department of Anatomy, AIIMS, Raipur, C.G.\u00a0University \u2013 AIIMS, Raipur, Chhattisgarh, India. E-Mail:<\/strong> dr.rathia@aiimsraipur.edu.in<\/p>\n

ABSTRACT<\/strong><\/p>\n

Introduction: <\/strong>Histogenesis of the human fetal kidney is the histological study of the maturity of the kidney at a given gestational age. Embryologically, the kidney is derived from the ureteric bud and the metanephric blastema. The ureteric bud forms the collecting part, and the metanephric blastema forms the secretory part. The details of the microscopic development of the kidney are not described in various textbooks of embryology.<\/p>\n

Methodology: <\/strong>50 aborted human fetuses between 13 to 36 weeks of gestational age without any gross congenital anomalies were included in the present study. Paraffin blocks of the cut sections of both\u00a0kidneys were prepared. Slides of 5\u20137 micron-thick sections stained with Masson\u2019s trichrome (MT) and Periodic acid-schiff (PAS) stains.<\/p>\n

Results and Conclusion: <\/strong>From 16 weeks onwards, the medulla showed well-differentiated collecting ducts, thick and thin segments of the loop of Henle. The amount of connective tissue decreased, and the vascularity of the medulla increased with an increase in gestational age. The transitional epithelium lining the renal pelvis was appreciated from 16 weeks onwards.\u00a0\u00a0<\/p>\n

KEYWORDS<\/strong>: Histogenesis, Kidney, Renal medulla, Gestational age, Masson\u2019s Trichrome stain, PAS stain.<\/p>\n

REFERENCES<\/strong><\/p>\n

[1]. Healy JC. Urogenital system in Standring S, editor. Gray’s anatomy: The Anatomical basis of Clinical Practice. 40th ed. London: Churchill Livingstone Elsevier; 2008. p. 1225-1313.
[2]. Dyson M. Urinary System in Williams PL, Bannister LH, Berry MM, Collins P, editors. Gray’s Anatomy. 38th ed. New York, Edinburgh, London: Churchill Livingstone; 1995.
[3]. Moore KL, Persaud TVN. The developing human: Clinically oriented embryology. 8th ed. Philadelphia: Saunders Elsevier; 2008. p. 243-56.
[4]. Hamilton WJ, Boyd, and Mossman. Human Embryology. 4th ed. The University of Michigan: Heffer Publication; 1972. p. 383-93.
https:\/\/doi.org\/10.1007\/978-1-349-02796-5
[5]. Sadler TW, editor. Langman’s Medical Embryology. 9th Ed. Baltimore: Lippincott Williams and Wilkins; 2006. p. 229-38.
[6]. Rahul Kisan Ukey, Reshma Baburao Shinde, Anil Shivshankar Rahule, Prafulla Nikam, C.V. Diwan. HISTOGENESIS OF HUMAN FETAL RENAL MEDULLA. Int J Anat Res 2018;6(3.2):5544-5549.
https:\/\/doi.org\/10.16965\/ijar.2018.277
[7]. Shalika Sharma, Sunanda Raina. STUDY OF HUMAN FETAL KIDNEY. Int J Anat Res 2014;2(4):785-790.
https:\/\/doi.org\/10.16965\/ijar.2014.550
[8]. Mishra S, Dinesh A, Kaul JM. Morphological and morphometric study of human renal development during the mid-gestational period. J Anat Soc India. 2006; 55(2): 5-10.
[9]. Tank KC, Saiyad SS, Pandya AM, Akbari VJ, Dangar KP. A study of histogenesis of human fetal kidney. Int J Biol Med Res. 2012; 3(1): 1315-21.
[10]. Patil S, Patil P, Mane A. Histogenesis Of Human Fetal Kidney. NJIRM. 2012 Jul-Aug; 3(3): 122-27.
[11]. Syed SA, Joshi RA, Herekar NG. Histogenesis of Kidney in Human Fetuses. International Journal of Recent Trends in Science and Technology. 2012; 3(2): 44-8.<\/p>\n

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\n \t Cite this article:<\/strong><\/span> Rahul Kisan Ukey, Dharam Singh Rathia, Tarkeshwar Devidas Golghate, Amit Purushottam Tirpude, Soumitra Trivedi.\u00a0Study of Histogenesis of Human Fetal Renal Medulla by Using Masson\u2019s Trichrome and PAS Stains.\u00a0 Int J Anat Res 2025;13(3):9332-9338. DOI:\u00a0<\/strong>10.16965\/ijar.2025.227\u00a0 \n <\/div>\t\n\t\t\n\n\n

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Type of Article: \u00a0Original Research Volume 13; Issue 3 (September 2025) Page No.: 9332-9338 DOI:\u00a0https:\/\/dx.doi.org\/10.16965\/ijar.2025.227 Study of Histogenesis of Human Fetal Renal Medulla by Using Masson\u2019s Trichrome and PAS Stains Rahul Kisan Ukey 1, Dharam Singh Rathia *2, Tarkeshwar Devidas Golghate 3, Amit Purushottam Tirpude 4, Soumitra Trivedi 5. 1 Assistant Professor, Department of Anatomy,
+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/3090"}],"collection":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/comments?post=3090"}],"version-history":[{"count":1,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/3090\/revisions"}],"predecessor-version":[{"id":3105,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/3090\/revisions\/3105"}],"wp:attachment":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/media?parent=3090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}