{"id":2914,"date":"2024-03-01T06:04:54","date_gmt":"2024-03-01T06:04:54","guid":{"rendered":"https:\/\/www.ijmhr.org\/IntJAnatRes\/?page_id=2914"},"modified":"2024-03-01T06:16:13","modified_gmt":"2024-03-01T06:16:13","slug":"ijar-2023-142","status":"publish","type":"page","link":"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2023-142","title":{"rendered":"IJAR.2023.142"},"content":{"rendered":"<div class=\"su-row\"><div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/www.ijmhr.org\/ijar.12.1\/IJAR.2023.142.pdf\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-cloud-download\" style=\"font-size:13px;color:#FFFFFF\"><\/i> DOWNLOAD PDF<\/span><\/a><\/div><\/div><\/div> <div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/ijmhr.org\/ijar-vol-12-1.htm\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-book\" style=\"font-size:13px;color:#FFFFFF\"><\/i> Table of Contents<\/span><\/a><\/div><\/div><\/div><\/div>\n<h3 style=\"text-align: justify;\"><strong>Type of Article:<\/strong> \u00a0Original Research<\/h3>\n<h3 style=\"text-align: justify;\"><strong>Volume 12; Issue 1 (March 2024)<\/strong><\/h3>\n<h3 style=\"text-align: justify;\"><strong>Page No.:<\/strong> 8800-8807<\/h3>\n<h3 style=\"text-align: justify;\"><strong>DOI:\u00a0<\/strong>https:\/\/dx.doi.org\/10.16965\/ijar.2023.142<\/h3>\n<h3 style=\"text-align: justify;\">Diffusion Weighted Imaging and Grading of Brain Tumours<\/h3>\n<p><strong>Manah Chandra Changmai *<sup>1a,1b<\/sup>, Mohammed Faruque Reza <sup>2<\/sup>, Kastury Gohain <sup>3<\/sup>.<\/strong><\/p>\n<p style=\"text-align: justify;\">*<sup>1a <\/sup>Lecturer, Centre for Anatomy and Human Identification, University of Dundee, Dundee, United Kingdom, <sup>b<\/sup> Universiti Sains, Malaysia. <strong>ORCiD: <\/strong>0000-0001-6440-2752<\/p>\n<p style=\"text-align: justify;\"><sup>2<\/sup> Senior Lecturer, Department of Neuroscience, School of Medicine, Universiti Sains Malaysia, Kubang kerian, Kelantan, Malaysia. <strong>ORCiD: <\/strong>0000-0002-0302-6623<\/p>\n<p><sup>3<\/sup> Lecturer, School of Business, University of Dundee, Dundee, United Kingdom.<strong>ORCiD: <\/strong>0000-0002-5190-8620<\/p>\n<p style=\"text-align: justify;\"><strong>Corresponding Author: <\/strong>Dr Manah Chandra Changmai, PhD Graduate Universiti Sains Malaysia, Malaysia. Lecturer, Centre for Anatomy and Human Identification, University of Dundee, Dundee, United Kingdom. <strong>E-Mail:<\/strong> manahchangmai@gmail.com<\/p>\n<p style=\"text-align: justify;\"><strong>ABSTRACT<\/strong>\u00a0<\/p>\n<p style=\"text-align: justify;\"><strong>Background:<\/strong> Most prevalent primary cerebral tumours are meningiomas. The other frequent intracranial tumours are pituitary adenomas, which are benign, and gliomas, which are intra-axial brain tumours. The objective of this study is to understand the importance of DW MRI imaging with standard b-value in differentiating presurgical grading of the brain tumour.<\/p>\n<p><strong>Design:<\/strong> A total of 24 DWI patients, including 12 meningiomas, 8 gliomas, and 4 pituitary adenomas, were included in this retrospective analysis.<\/p>\n<p style=\"text-align: justify;\"><strong>Method:<\/strong> The Stejskal-Tanner equation is used to analyse the ADC<sub>mean<\/sub>, ADC<sub>min<\/sub>, and ADC<sub>max<\/sub> values from the healthy and tumour core that are obtained out from area of interest (ROI).<\/p>\n<p style=\"text-align: justify;\"><strong>Result:<\/strong> The ADC<sub>mean<\/sub> value of Gliomas ranges from 0.09 x 10<sup>-3<\/sup> mm<sup>2<\/sup>s<sup>-1<\/sup> to 0.99 x 10<sup>-3<\/sup> mm<sup>2<\/sup>s<sup>-1<\/sup> with a median value of 0.25 x 10<sup>-3<\/sup> mm<sup>2<\/sup>s<sup>-1<\/sup>. ADC<sub>mean<\/sub> value 1.82 x 10<sup>-3<\/sup> mm<sup>2<\/sup>\/s (sensitivity: 67%. Specificity: 81.8%) and 0.94 x 10<sup>-3<\/sup> mm<sup>2<\/sup>\/s (sensitivity: 75%. specificity: 81.3%) can discriminate grade II \u2013IV meningioma from grade II-IV glioma.<\/p>\n<p style=\"text-align: justify;\"><strong>Conclusion<em>:<\/em><\/strong> The ADC and its threshold levels offer crucial details on the grades, consistency, and characterization of tumour, aiding accurate diagnosis and therapy.<\/p>\n<p><strong>Keywords:<\/strong> Brain tumour, Imaging, MRI, DWI, ADC, b-value.<\/p>\n<p style=\"text-align: justify;\"><strong>REFERENCES<\/strong><\/p>\n<p style=\"text-align: justify;\">[1]. Ostrom QT, Ph D, Gittleman H, Truitt G, Boscia A, Kruchko C, et al. Neuro-Oncology CBTRUS Statistical Report\u202f: Primary Brain and Other Central Nervous System Tumors Diagnosed in the. 2018;20:1-86.<br \/>https:\/\/doi.org\/10.1093\/neuonc\/noy131<br \/>PMid:30445539 PMCid:PMC6129949 <br \/>[2]. 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J Clin Imaging Sci. 2011;1(1):1-7.<br \/>https:\/\/doi.org\/10.4103\/2156-7514.81294<br \/>PMid:21966624 PMCid:PMC3177415<\/p>\n<p style=\"text-align: justify;\">\n\t\t\t <div class=\"promo1\" style=\"background-color:#f7f7f7; border-color: #6b0e00 #e8e6e6 #e8e6e6;\">\n             \t <span style=\"color: #800000;\"><strong>Cite this article:<\/strong><\/span> Manah Chandra Changmai, Mohammed Faruque Reza, Kastury Gohain. Diffusion Weighted Imaging and Grading of Brain Tumours. Int J Anat Res 2024;12(1):8800-8807. <strong>DOI:\u00a0<\/strong>10.16965\/ijar.2023.142\u00a0 \n             <\/div>\t\n\t\t\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of Article: \u00a0Original Research Volume 12; Issue 1 (March 2024) Page No.: 8800-8807 DOI:\u00a0https:\/\/dx.doi.org\/10.16965\/ijar.2023.142 Diffusion Weighted Imaging and Grading of Brain Tumours Manah Chandra Changmai *1a,1b, Mohammed Faruque Reza 2, Kastury Gohain 3. *1a Lecturer, Centre for Anatomy and Human Identification, University of Dundee, Dundee, United Kingdom, b Universiti Sains, Malaysia. ORCiD: 0000-0001-6440-2752 2<br \/><a class=\"moretag\" href=\"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2023-142\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2914"}],"collection":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/comments?post=2914"}],"version-history":[{"count":2,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2914\/revisions"}],"predecessor-version":[{"id":2917,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2914\/revisions\/2917"}],"wp:attachment":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/media?parent=2914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}