{"id":2802,"date":"2023-06-04T16:56:23","date_gmt":"2023-06-04T16:56:23","guid":{"rendered":"https:\/\/www.ijmhr.org\/IntJAnatRes\/?page_id=2802"},"modified":"2023-06-04T16:56:23","modified_gmt":"2023-06-04T16:56:23","slug":"ijar-2023-103","status":"publish","type":"page","link":"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2023-103","title":{"rendered":"IJAR.2023.103"},"content":{"rendered":"<div class=\"su-row\"><div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/www.ijmhr.org\/ijar.11.2\/IJAR.2023.103.pdf\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-cloud-download\" style=\"font-size:13px;color:#FFFFFF\"><\/i> DOWNLOAD PDF<\/span><\/a><\/div><\/div><\/div> <div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/ijmhr.org\/ijar-vol-11-2.htm\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-book\" style=\"font-size:13px;color:#FFFFFF\"><\/i> Table of Contents<\/span><\/a><\/div><\/div><\/div><\/div>\n<h3 style=\"text-align: justify;\"><strong>Type of Article:<\/strong> \u00a0Original Research<\/h3>\n<h3 style=\"text-align: justify;\"><strong>Volume 11; Issue 2 (June2023)<\/strong><\/h3>\n<h3 style=\"text-align: justify;\"><strong>Page No.:<\/strong> 8600-8609<\/h3>\n<h3 style=\"text-align: justify;\"><strong>DOI:\u00a0<\/strong>https:\/\/dx.doi.org\/10.16965\/ijar.2023.103<\/h3>\n<h3 style=\"text-align: justify;\">Prostate Gland in Human Foetuses: A Study of its Histogenesis<\/h3>\n<p style=\"text-align: justify;\"><strong>Renuca Karam *<sup>1<\/sup>, Rajshree Huidrom <sup>2<\/sup>, Subhalakshmi Wahengbam <sup>3<\/sup>, Damayanti Ningthoujam <sup>4<\/sup>, Saratchandra N <sup>5<\/sup>.<\/strong><\/p>\n<p style=\"text-align: justify;\"><sup>*1<\/sup> Associate Professor, Dept. of Anatomy, Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India.<\/p>\n<p style=\"text-align: justify;\"><sup>2<\/sup> Associate Professor, Dept. of Anatomy, Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India.<\/p>\n<p style=\"text-align: justify;\"><sup>3<\/sup> Professor, Dept. of Anatomy, Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India.<\/p>\n<p><sup>4<\/sup> Professor and Head, Dept. of Anatomy, Churachandpur Medical College, Manipur, India.<\/p>\n<p style=\"text-align: justify;\"><sup>5<\/sup> Professor and Head, Dept. of Anatomy, Shija Academy of Health Sciences, Imphal, Manipur, India.<\/p>\n<p style=\"text-align: justify;\"><strong>Corresponding Author:\u00a0<\/strong>Dr. Renuca Karam, Associate Professor, Department of Anatomy, Jawaharlal Nehru Institute of Medical Sciences, (JNIMS), Porompat, Imphal-795005, Manipur, India. Mobile no. (+91) 8974054027\u00a0<strong>E-Mail: <a href=\"mailto:krenuca@gmail.com\">krenuca@gmail.com<\/a><\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>ABSTRACT<\/strong>\u00a0<\/p>\n<p style=\"text-align: justify;\"><strong>Background:<\/strong> To study the histogenesis of the prostate gland in human foetuses. \u2018Prostates\u2019 is a Greek word which literally means \u201cone who stands before\u201d, protector, guardian. It is important from a clinical point of view as it undergoes benign enlargement from the fifth decade, hence attracting the attention of males around this age and simultaneously the clinicians.<\/p>\n<p style=\"text-align: justify;\"><strong>Materials and Methods:<\/strong> 100 foetuses of different gestational ages ranging from 14 weeks (85 mm) to 40 weeks (440 mm), products of terminated pregnancies under Medical Termination of Pregnancy, MTP Act of India, 1971 and stillbirths were collected from the Department of Obstetrics and Gynaecology, RIMS, (Regional Institute of Medical Sciences), Imphal, Manipur and utilised for the present study with permission from the Institutional Ethical Committee.<\/p>\n<p style=\"text-align: justify;\"><strong>Results and Discussion:<\/strong> The first sign of differentiation is recognised as increased cellularity and denser mesenchymal cells. Cytoarchitecture at specific age period at different age groups are described.<\/p>\n<p style=\"text-align: justify;\"><strong>Conclusion:<\/strong> Cytoarchitecturally, differentiation of all three components of the prostate gland was noted as the age changes. It is inferred that of the three components of the adult tissues, the glandular component is differentiated from the epithelial lining of the urethra. This further induces the early mesenchymal tissues to differentiate into muscles and fibrous components. And at term, it has all three components of the adult tissues although it is not as mature as in adults.<\/p>\n<p><strong>\u00a0KEY WORDS:<\/strong> Prostate gland, human foetuses, histogenesis, and cytoarchitecture.<\/p>\n<p style=\"text-align: justify;\"><strong>REFERENCES<\/strong><\/p>\n<p style=\"text-align: justify;\">[1]. Leeson CR, Leeson TS, Paparo AA. In: Textbook of histology. 5th ed. Philadelphia: WB Saunders Company; 1985. p. 492-517.<br \/>[2]. Skandalakis JE, Colborn GL, Badalament RA, Scaljon W, Parrott TS, Galloway NTM et al. Male genital system. Skandalakis JE, Weidman TA, Colborn GL. editors. In: Skandalakis Surgical Anatomy. 1st ed. Greece: Paschalidis Medical Publications Ltd; 2004. p. 1415-38.<br \/>[3]. Wein AJ. Normal development of the urogenital system. Kavoussi LR, Novide AC, Partin AW, Peters CA. editors. In pediatric urology. Vol 4. 9th ed. Philadelphia: Saunders Elsevier; 2007. p. 3137-9. <br \/>[4]. Joesting MS, Cheever TR, Volging KG, Yamaguchi TP, Wolf V, Naf D, et al. Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching, morphogenesis, proliferation and secretory gene expression in the prostate. Dev Biol. 2008; 317(1):161-73. <br \/>[5]. Structure of the prostate gland. Available from-<br \/>http:\/\/www.ana.ed.ac.uk\/database\/prosbase\/proshome.html. Accessed date: 14.09.2010.<br \/>[6]. Standring S. Prostate. Ellis H, Healy JC, Johnson D, Williams A. editors. In: Gray\u2019s Anatomy: the anatomical basis of clinical practice. 39th ed. London: Churchill Livingstone; 2005. p. 1301-4.<br \/>[7]. Larsen WJ. Development of the urogenital system. In: Human embryology. 3rd ed. Philadelphia: Churchill Livingstone; 2001. p. 282-3.<br \/>[8]. Glenister TW. The development of the utricle and the so called median or middle lobe of the human prostate. J. Anat. 1962; 96(4):443-55. <br \/>[9]. Andrews GS. In: The histology of the human fetal and prepubertal prostates. J Anat.1951; 85(1):44-54. <br \/>[10]. Ross MH, Pawlina W. Male reproductive system. In: Histology-A Text and Atlas. 5th ed. Philadelphia: Lippincott Williams and Wilkins; 2006. p. 752.<br \/>[11]. Snell RS. The pelvis: part II: The pelvic cavity. In: clinical anatomy. 7th ed. Philadelphia: Lippincott Williams and Wilkins; 1993. p. 317-39.<br \/>[12]. Sahana SN. Genital System In: Human Anatomy. 3rd edition. India: Books and Allied Private Limited; 1980. p. 402-5.<br \/>[13]. Moore KL, Agur AMR. Male internal genital system. In: Betty Sun, Dana Battagli, editors. Essential clinical anatomy. 3rd ed. Philadelphia: Lippincott Williams and Wilkins; 2007. p. 230-40.<br \/>[14]. Buchanon G. In: Human anatomy (Descriptive and Applied).3rd ed. India: Books and Allied private limited; 1980. p. 402-5. <br \/>[15]. Sinnatamby CS. Male internal genital organs. In: Timothy Horne, Hannah Kenner, editors. Last\u2019s Anatomy: regional and applied. 11th ed. New York: Churchill Livingstone; 2006. p. 229-36.<br \/>[16]. Hammerich KH, Ayala GE, Wheeler TM. Anatomy of the prostate gland and surgical pathology of prostate cancer. In: Hedvig Hricak, Scardino PT, editors. Prostate Cancer. New York: Cambridge University Press; 2009. <br \/>[17]. Bevelander G, Ramalay JA. Male reproductive system. In: Essentials of histology. Saint Louis: CV Mosby Company; 1974. p. 269-71.<br \/>[18]. Swyer GIM. Postnatal growth changes in the human prostate. J Anat. 1944; 78(4):130-145.<br \/>[19]. Neal MC. Normal histology of the prostate. Am J Surg Pathol 1988; 12(8):619-33.<br \/>[20]. Lentinen K, Santti R, Penlliniemi LJ. Correlation of early cytodifferentiation of the human fetal prostate and Leydig cells. Anat Rec.1980; 196(3):263-73.<br \/>[21]. Copenhaver WM, Kelly DE, Wood RL. The male reproductive system. In: Bailey\u2019s textbook of histology. 17th ed. Baltimore: Williams and Wilkins; 1978. p. 637-638.<br \/>[22]. BloomW, Fawcett DW. In: A textbook of histology. 10th ed. Philadelphia: WB Saunders Company; 1976. p. 805-55.<br \/>[23]. Cormack DH. Male reproductive system. In: Robert Anthony, Eric Branger, editors. Essential histology. 2nd ed. Philadelphia: Lippincott Williams and Wilkins; 2001. p. 250-65.<\/p>\n<p style=\"text-align: justify;\">\n\t\t\t <div class=\"promo1\" style=\"background-color:#f7f7f7; border-color: #6b0e00 #e8e6e6 #e8e6e6;\">\n             \t <span style=\"color: #800000;\"><strong>Cite this article:<\/strong><\/span> Renuca Karam, Rajshree Huidrom, Subhalakshmi Wahengbam, Damayanti Ningthoujam, Saratchandra N. Prostate Gland in Human Foetuses: A Study of its Histogenesis. Int J Anat Res 2023;11(2):8600-8609. <strong>DOI:\u00a0<\/strong>10.16965\/ijar.2023.103\u00a0 \n             <\/div>\t\n\t\t\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of Article: \u00a0Original Research Volume 11; Issue 2 (June2023) Page No.: 8600-8609 DOI:\u00a0https:\/\/dx.doi.org\/10.16965\/ijar.2023.103 Prostate Gland in Human Foetuses: A Study of its Histogenesis Renuca Karam *1, Rajshree Huidrom 2, Subhalakshmi Wahengbam 3, Damayanti Ningthoujam 4, Saratchandra N 5. *1 Associate Professor, Dept. of Anatomy, Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India. 2<br \/><a class=\"moretag\" href=\"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2023-103\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2802"}],"collection":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/comments?post=2802"}],"version-history":[{"count":1,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2802\/revisions"}],"predecessor-version":[{"id":2803,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2802\/revisions\/2803"}],"wp:attachment":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/media?parent=2802"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}