{"id":2322,"date":"2020-07-05T14:27:58","date_gmt":"2020-07-05T14:27:58","guid":{"rendered":"http:\/\/www.ijmhr.org\/IntJAnatRes\/?page_id=2322"},"modified":"2020-07-06T02:53:20","modified_gmt":"2020-07-06T02:53:20","slug":"ijar-2020-175","status":"publish","type":"page","link":"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2020-175","title":{"rendered":"IJAR.2020.175"},"content":{"rendered":"
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Type of Article:<\/strong>\u00a0\u00a0Original Research<\/h3>\n

Volume 8; Issue 3.1 (July 2020)<\/strong><\/h3>\n

Page No.:<\/strong>\u00a07621-7632<\/h3>\n

DOI:\u00a0<\/strong>https:\/\/dx.doi.org\/10.16965\/ijar.2020.175<\/h3>\n

FETAL SKELETAL GROWTH PATTERN ANALYSIS IN FETUSES WITH SKELETAL DYSPLASIA\u2013 AN ULTRASONOGRAPHY STUDY IN WESTERN INDIAN POPULATION<\/h3>\n

Rakesh Kumar Jha 1 <\/sup>, Charmode Sundip Hemant *2<\/sup>.<\/strong><\/p>\n

1<\/sup> Department of Anatomy, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.<\/p>\n

*2 <\/sup>Department of Anatomy, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.<\/p>\n

Corresponding author:<\/strong> Dr. Charmode Sundip Hemant, Department of Anatomy, All India Institute of Medical Sciences, Kunraghat, Gorakhpur, Uttar Pradesh, India -273008\u00a0E-Mail:<\/strong> sundip.charmode@yahoo.com<\/p>\n

ABSTRACT<\/h3>\n

Background:\u00a0<\/strong>In developing countries like India, several genetic, environmental factors and diverse\u00a0cultural practices affect the normal growth and development of human embryo resulting in congenital malformations namely skeletal dysplasia. This article aims at analyzing the fetal skeletal growth pattern followed by its correlation to understand prenatal diagnosis of\u00a0 skeletal dysplasia.<\/p>\n

Materials and Methods:\u00a0<\/strong>Two studies, conducted by the authors at different places in western India population have been \u00a0correlated. Primary prospective study, was\u00a0conducted among\u00a0500 antenatal women coming for routine antenatal check-up during from 1st<\/sup>\u00a0July 2015 to 31st<\/sup>\u00a0May 2018. Routine fetal parameters like biparietal diameter, gestational sac, HC,\u00a0AC, TC, FL along with all the other fetal long bones were measured using 2D\/3D ultrasonography. Second retrospective study, was conducted on new-borns with congenital malformations in the same population.\u200b<\/p>\n

Result:\u00a0<\/strong>Out\u00a0of the total 10,114 deliveries conducted during the study\u00a0period, 182 new-borns\u00a0 had congenital malformations, out of which 23 cases had\u00a0skeletal dysplasia. Fetal skeletal growth pattern analysis done was observed to be comparable with other populations residing in different parts\u00a0of India and also abroad.\u00a0\u00a0\u00a0Thanatophoric dysplasia was the most common type of skeletal dysplasia. Prenatal diagnosis of skeletal dysplasia\u00a0was done correctly in 75% of cases. Peak\u00a0 of diagnoses were between 15 and 19 weeks of\u00a0gestational age.<\/p>\n

Conclusions:\u00a0<\/strong>Fetal growth pattern\u00a0analysis observed in western Indian population is similar to that observed in other groups of India and abroad.\u00a0In majority of cases of thanatophoric dysplasia, prenatal ultrasound examination was diagnostic, providing a correct diagnosis using ultrasonography as the sole modality.<\/p>\n

Key words:<\/strong> Skeletal Dysplasia, Prenatal Diagnosis, Fetal Growth Analysis, Thanatophoric\u00a0 Dysplasia.<\/p>\n

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    \n \t Cite this article:<\/strong><\/span> Rakesh Kumar Jha, Charmode Sundip Hemant. FETAL SKELETAL GROWTH PATTERN ANALYSIS IN FETUSES WITH SKELETAL DYSPLASIA\u2013 AN ULTRASONOGRAPHY STUDY IN WESTERN INDIAN POPULATION. Int J Anat Res 2020;8(3.1):7621-7632.\u00a0DOI:\u00a0<\/strong>10.16965\/ijar.2020.175\u00a0 \n <\/div>\t\n\t\t\n","protected":false},"excerpt":{"rendered":"

    Type of Article:\u00a0\u00a0Original Research Volume 8; Issue 3.1 (July 2020) Page No.:\u00a07621-7632 DOI:\u00a0https:\/\/dx.doi.org\/10.16965\/ijar.2020.175 FETAL SKELETAL GROWTH PATTERN ANALYSIS IN FETUSES WITH SKELETAL DYSPLASIA\u2013 AN ULTRASONOGRAPHY STUDY IN WESTERN INDIAN POPULATION Rakesh Kumar Jha 1 , Charmode Sundip Hemant *2. 1 Department of Anatomy, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India. *2 Department
    + Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2322"}],"collection":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/comments?post=2322"}],"version-history":[{"count":2,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2322\/revisions"}],"predecessor-version":[{"id":2328,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2322\/revisions\/2328"}],"wp:attachment":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/media?parent=2322"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}