{"id":2106,"date":"2019-11-05T14:35:13","date_gmt":"2019-11-05T14:35:13","guid":{"rendered":"http:\/\/www.ijmhr.org\/IntJAnatRes\/?page_id=2106"},"modified":"2019-11-05T14:35:13","modified_gmt":"2019-11-05T14:35:13","slug":"ijar-2019-317","status":"publish","type":"page","link":"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2019-317","title":{"rendered":"IJAR.2019.317"},"content":{"rendered":"<div class=\"su-row\"><div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/www.ijmhr.org\/ijar.7.4\/IJAR.2019.317.pdf\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-cloud-download\" style=\"font-size:13px;color:#FFFFFF\"><\/i> DOWNLOAD PDF<\/span><\/a><\/div><\/div><\/div> <div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/ijmhr.org\/ijar-vol-7-4.htm\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-book\" style=\"font-size:13px;color:#FFFFFF\"><\/i> Table of Contents<\/span><\/a><\/div><\/div><\/div><\/div>\n<h3 style=\"text-align: justify;\"><strong>Type of Article:<\/strong>\u00a0\u00a0Original Research<\/h3>\n<h3 style=\"text-align: justify;\"><strong>Volume 7; Issue 4.2 (November 2019)<\/strong><\/h3>\n<h3 style=\"text-align: justify;\"><strong>Page No.:<\/strong>\u00a07119-7122<\/h3>\n<h3 style=\"text-align: justify;\"><strong>DOI:\u00a0<\/strong>https:\/\/dx.doi.org\/10.16965\/ijar.2019.317<\/h3>\n<h3 style=\"text-align: justify;\">STUDY OF CHANGES IN COLOUR AND MORPHOLOGICAL PARAMETERS IN HUMAN CATARACTOUS LENS NUCLEI<\/h3>\n<p style=\"text-align: justify;\"><strong>Shashank Vedpathak *<sup>1<\/sup>, S.S. Dhapate <sup>2<\/sup>, Sandeep Bendale <sup>3<\/sup>.<\/strong><\/p>\n<p style=\"text-align: justify;\"><sup>*1<\/sup> Associate Professor, Department of Anatomy , MIMER Medical College, Talegaon, Dabhade, Pune, Maharashtra, India.<\/p>\n<p style=\"text-align: justify;\"><sup>2<\/sup>Professor and HOD, Department of Anatomy, S.R.T.R. Medical College, Ambajogai, Maharashtra, India.<\/p>\n<p style=\"text-align: justify;\"><sup>3<\/sup> Assistant Professor, Department of Radiodiagnosis, MIMER Medical College, Talegaon, Dabhade, Pune, Maharashtra, India.<\/p>\n<p style=\"text-align: justify;\"><strong>Corresponding Author:<\/strong> Dr Shashank Vedpathak, Department of Anatomy, MIMER Medical College, Talegaon Dabhade, Pune, Maharashtra, India. Mobile no \u2013 9604200292\u00a0<strong>E-Mail:<\/strong> sbvedpathak@gmail.com<\/p>\n<p style=\"text-align: justify;\"><strong>ABSTRACT:<\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Introduction: <\/strong>Opacification of the lens of the eye which makes it blind is called cataract. This study deals with the cataractous lenses removed from the patients residing in a rural area like marathwada region and was done at S.R.T.R. Medical College Ambajogai. This topic was chosen as this type of study has never been done before in this region. From anatomical point of view the morphologic features of the lens nuclei removed by extracapsular cataract extraction method are studied and compared with age and sex of patient.<\/p>\n<p style=\"text-align: justify;\"><strong>Materials and methods: <\/strong>The lens nuclei removed by extracapsular extraction method were collected in plain bulbs and preserved in 10% formalin for morphological observations. Detailed case history of the patient is recorded. Colour of lens nuclei was recorded and changes in diameter, thickness and wet weight of lens nuclei according to colour were studied. Diameter and thickness was measured with vernier caliper while weight is measured with two pan scientific balance. Pirie\u2019s classification was used to divide the lens in four groups.<\/p>\n<p style=\"text-align: justify;\"><strong>Results<\/strong>: According to our study mean diameter of lens nuclei goes on increasing from Group I to Group IV in both men and women and similar findings are observed for mean thickness and weight of lens nuclei in both male and female.<\/p>\n<p style=\"text-align: justify;\"><strong>Discussion<\/strong>: Our study found statistically significant increase in thickness, diameter and weight of lens as the colour of lens nuclei deepens. Our findings are compared with other workers. These morphological findings may be useful for the ophthalmologists to correlate with their clinical observations.<\/p>\n<p style=\"text-align: justify;\"><strong>Conclusion<\/strong>: Our study found that morphological parameters of lens change as its colour deepens.<\/p>\n<p style=\"text-align: justify;\"><strong>Key words<\/strong>: Colour, Cataract, Diameter, Lens, Thickness, Weight.<\/p>\n<p style=\"text-align: justify;\"><strong>REFERENCES<\/strong><\/p>\n<ol>\n<li style=\"text-align: justify;\">Adler\u2019s Physiology of Eye.The Lens, in: Adler\u2019s Physiology of Eye by Christopher A. Paterson, Nicholas Delamere, 348-390.<\/li>\n<li style=\"text-align: justify;\">Shah L. M., Lipid profile in normal human &amp; senile cataractous lenses, a dissertation submitted for the Medical Biochemistry degree examination of University of Pune.<\/li>\n<li style=\"text-align: justify;\">Costello M. J., Oliver T. N., Cobo LM.; Cellular architecture in age-related human nuclear cataracts. Invest Ophthalmol Vis Sci. 1992 Oct; 33(11):3209-27.<\/li>\n<li style=\"text-align: justify;\">J. Harding; Free &amp; protein bound glutathione in normal and cataractous lenses Biochem J, 1970;117:957-960.<\/li>\n<li style=\"text-align: justify;\">Antoinette Pirie; Colour &amp; solubility of proteins of human cataracts.Invest Opthalmol Vis Sci, 1968 Dec; 634-650.<\/li>\n<li style=\"text-align: justify;\">Taylor V. L., al-Ghoul K. J., Lane C. W., Davis V. A., Kuszak J. R., Costello M. J.<br \/>Morphology of the normal human lens. Invest Ophthalmol Vis Sci. 1996 Jun; 37(7):1396-410.<\/li>\n<li style=\"text-align: justify;\">Tabandeh H., Thompson G. M., Heyworth P. Lens hardness in mature cataract Eye 1994; 8(4):453-5.<\/li>\n<li style=\"text-align: justify;\">Dorairaj, S. J., Vatsala V, Vijaya Kumar J, Kesavai R, Sucheethra D.S., Vidyasree, S. Morphometric and Histological Study of Human Cataract Lens; Journal of Anatomical Society of India. 2002;51(1):14-17.<\/li>\n<li style=\"text-align: justify;\">Gullapalli Vamsi Krishna, Murthy Praveen R, Murthy K. R.; Colour of the nucleus as a marker of nuclear hardness, diameter and central thickness, Indian J Ophthalmol 1995;43:181-184.<\/li>\n<li style=\"text-align: justify;\">Hu C, Zhang X, Hui Y. The nuclear hardness and associated factors of age-related cataract ; Jpn J ophthalmol. 1997;37(4):467-77.<\/li>\n<\/ol>\n<p style=\"text-align: justify;\">\n\t\t\t <div class=\"promo1\" style=\"background-color:#f7f7f7; border-color: #6b0e00 #e8e6e6 #e8e6e6;\">\n             \t <span style=\"color: #800000;\"><strong>Cite this article:<\/strong><\/span> Shashank Vedpathak, S.S. Dhapate, Sandeep Bendale. STUDY OF CHANGES IN COLOUR AND MORPHOLOGICAL PARAMETERS IN HUMAN CATARACTOUS LENS NUCLEI. Int J Anat Res 2019;7(4.2):7119-7122.\u00a0<strong>DOI:\u00a0<\/strong>10.16965\/ijar.2019.317\u00a0 \n             <\/div>\t\n\t\t\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Type of Article:\u00a0\u00a0Original Research Volume 7; Issue 4.2 (November 2019) Page No.:\u00a07119-7122 DOI:\u00a0https:\/\/dx.doi.org\/10.16965\/ijar.2019.317 STUDY OF CHANGES IN COLOUR AND MORPHOLOGICAL PARAMETERS IN HUMAN CATARACTOUS LENS NUCLEI Shashank Vedpathak *1, S.S. Dhapate 2, Sandeep Bendale 3. *1 Associate Professor, Department of Anatomy , MIMER Medical College, Talegaon, Dabhade, Pune, Maharashtra, India. 2Professor and HOD, Department of<br \/><a class=\"moretag\" href=\"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2019-317\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2106"}],"collection":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/comments?post=2106"}],"version-history":[{"count":1,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2106\/revisions"}],"predecessor-version":[{"id":2111,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/2106\/revisions\/2111"}],"wp:attachment":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/media?parent=2106"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}