{"id":1625,"date":"2018-12-05T14:28:53","date_gmt":"2018-12-05T14:28:53","guid":{"rendered":"http:\/\/www.ijmhr.org\/IntJAnatRes\/?page_id=1625"},"modified":"2018-12-05T14:29:54","modified_gmt":"2018-12-05T14:29:54","slug":"ijar-2018-390","status":"publish","type":"page","link":"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2018-390","title":{"rendered":"IJAR.2018.390"},"content":{"rendered":"<div class=\"su-row\"><div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/www.ijmhr.org\/ijar.6.4\/IJAR.2018.390.pdf\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-cloud-download\" style=\"font-size:13px;color:#FFFFFF\"><\/i> DOWNLOAD PDF<\/span><\/a><\/div><\/div><\/div> <div class=\"su-column su-column-size-1-2\"><div class=\"su-column-inner su-u-clearfix su-u-trim\"><div class=\"su-button-center\"><a href=\"https:\/\/ijmhr.org\/ijar-vol-6-4.htm\" class=\"su-button su-button-style-default\" style=\"color:#FFFFFF;background-color:#6b0e00;border-color:#560c00;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px\" target=\"_self\"><span style=\"color:#FFFFFF;padding:6px 16px;font-size:13px;line-height:20px;border-color:#98574d;border-radius:5px;-moz-border-radius:5px;-webkit-border-radius:5px;text-shadow:none;-moz-text-shadow:none;-webkit-text-shadow:none\"><i class=\"sui sui-book\" style=\"font-size:13px;color:#FFFFFF\"><\/i> Table of Contents<\/span><\/a><\/div><\/div><\/div><\/div>\n<h3 style=\"text-align: justify;\"><strong>Type of Article:<\/strong>\u00a0\u00a0Original Research<\/h3>\n<h3 style=\"text-align: justify;\"><strong>Volume 6; Issue 4.3 (December 2018)<\/strong><\/h3>\n<h3 style=\"text-align: justify;\"><strong>Page No.:<\/strong>\u00a05983-5988<\/h3>\n<h3 style=\"text-align: justify;\"><strong>DOI:\u00a0<\/strong>https:\/\/dx.doi.org\/10.16965\/ijar.2018.390<\/h3>\n<h3 style=\"text-align: justify;\">MORPHOMETRIC STUDY OF HUMAN FOETAL SPLEEN: A STUDY FROM NORTH-INDIA<\/h3>\n<p style=\"text-align: justify;\"><strong>Kuntal Vashishtha *<sup>1<\/sup>, Vinayak Gaur <sup>2<\/sup>, Kanchan Kapoor <sup>3<\/sup>.<\/strong><\/p>\n<p><sup>*1 <\/sup>Assistant Professor Anatomy, Dr. Y.S. Parmar Govt. medical college Nahan, Himachal Pradesh, India.<\/p>\n<p><sup>2<\/sup> Assistant Professor Anatomy,J.L.N. medical college, Ajmer, Rajasthan, India.<\/p>\n<p><sup>3<\/sup> Professor of Anatomy, GMCH, Chandigarh, India.<\/p>\n<p style=\"text-align: justify;\"><strong>Address for correspondence:<\/strong> Dr Kuntal Vashishtha, Assistant Professor Anatomy, Dr. Y.S. Parmar Govt. medical college Nahan, Himachal Pradesh, India. Mobile \u2013 8360267662, 9815447045 <strong>E-Mail:<\/strong> kuntalvashishtha@ymail.com<\/p>\n<p style=\"text-align: justify;\"><strong>ABSTRACT:<\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Background:<\/strong> The vertebrate spleen has important functions in immunity and haematopoiesis, many of which have been well studied. In contrast, we know very less about the mechanisms governing its early embryonic development. There is little research on morphomertric analysis of spleen in human fetal cadavers.<\/p>\n<p style=\"text-align: justify;\"><strong>Aims and objectives: <\/strong>The \u00a0present study was carried out to determine the location and dimensions of human fetal spleen.<\/p>\n<p style=\"text-align: justify;\"><strong>Material and methods:<\/strong> The study was carried out on 50 dead human fetal spleens (30 males and 20 females), aged between 9 &#8211; 32 weeks of gestation. The location of spleen and its relation with the neighboring structures,\u00a0 notches on \u00a0borders, major ligaments and the shape of spleen and its hilum were studied. The length, width, thickness, and weight of the spleen were measured.<\/p>\n<p style=\"text-align: justify;\"><strong>Results: <\/strong>The average length, width and thickness of fetal spleen of gestational age between 12 to 16 weeks were\u00a0 7.65mm, 4.71mm, 2.93mm. respectively and mean weight was.065gm.\u00a0 In &gt;16 to 20 weeks, mean length was 10.9mm, width was 7.05mm, thickness was 5mm. respectively and weight was 0.461gm. In &gt;20 to 24 weeks, mean length was 13.45mm,width was 8.38m , thickness was 5.72mm. and weight was.580gm.\u00a0 In &gt;24 to 28 weeks, mean length was 19.8mm, width was 12.43mm, thickness was 8.67mm.and weight was .997gm. In &gt;28 weeks gestational age , mean length was 26.5mm, width was 13.5mm, thickness was 9.2mm.and weight was 1.91gm.\u00a0 Spleen was found to be of three different shapes &#8211; leaf shaped (two faced), wedge shaped (three faced) and pyramid shaped (four faced). In 44 cases (88%) it was wedge shaped, in four cases (8%) it was two faced and in two cases (4%) it was pyramid shaped.<\/p>\n<p style=\"text-align: justify;\"><strong>Conclusion:<\/strong> The expression of morphometric parameters of the spleen at different gestational ages can be used in determining various pathologies of the spleen and may also contribute to future studies on this subject.<\/p>\n<p style=\"text-align: justify;\"><strong>Key words:<\/strong> Fetal Spleen, Morphomertric Data, Splenic Development.<\/p>\n<p style=\"text-align: justify;\"><strong>REFERENCES<\/strong><\/p>\n<ol>\n<li style=\"text-align: justify;\">Moore KL, Dalley AF. Clinically oriented anatomy 4<sup>th<\/sup> ed Lippincott Williams and Wilkins Maryland. 1999;256-271.<\/li>\n<li style=\"text-align: justify;\">Brendolan A, Rosado MM,Carsetti R,Selleri L,Dear TN. Development and function of the mammalian spleen. Bioessays 2007Feb;29(2):166-77.<\/li>\n<li style=\"text-align: justify;\">Gray\u2018s Anatomy 38th edition. Churchill Livingstone. 1995:1437-45pp<\/li>\n<li style=\"text-align: justify;\">Hamilton WJ,Mossman . Human Embryology \u2013Prenatal development of form and function.4<sup>th<\/sup> edition 1972:363-64.<\/li>\n<li style=\"text-align: justify;\">Schmidt W. Yarkoni S .Jeanty P. Grannum P, Hobbins John. Sonographic measurements of the fetal spleen: clinical implications. J. Ultrasound Med. 1985;4:667 -672.<\/li>\n<li style=\"text-align: justify;\">Hata T, Deter RL, Aoki S, Makahara K, Hata K, Kitao M. Mathematical modeling of fetal splenic growth : use of the Rossavik growth model : J. Clin. Ultrasound 1992;20:321-327.<\/li>\n<li style=\"text-align: justify;\">Aoki S, Hata T, Kitao M. Ultrasonographic assessment of fetal and neonatal spleen. Am J Perinatol 1992;9:361-367.<\/li>\n<li style=\"text-align: justify;\">Griffith RC,Junney CG. Haemopoietic system ,Bone marrow and blood ,spleen and lymph nodes. In: Kissane JM (ed)Anderson\u2019s pathology,vol.2, 9<sup>th<\/sup> St.Louis,Mosby .1985;1408.<\/li>\n<li style=\"text-align: justify;\">Ungor B, Malas MA, Sulak O, Albay S. Development of spleen during the fetal period. Surg Radiol Anat. 2007 Oct; 29(7):543-50.<\/li>\n<li style=\"text-align: justify;\"><strong>Shaik Hussain Saheb, Subhadra Devi Velichety, Haseena S. Morphological And Morphometric Study of Human Foetal Spleen. <\/strong>Int J Anat Res 2014;2(1):234-238.<\/li>\n<li style=\"text-align: justify;\"><strong>Singh R, Kumari G.<\/strong> Morphological assessment of human foetal spleen. Asian J Biomed Pharmaceut Sci: 2016;6(52):19-21.<\/li>\n<li style=\"text-align: justify;\">Skandalakis P, Colborn GL, Skandalakis LJ, Richardson DD, Mitchell WE, Skandalakis JE . The surgical anatomy of the Surg Clin North Am 1993;73(4):747\u2013767.<\/li>\n<li style=\"text-align: justify;\">Soyluoglu A\u00c3, Tanyeli E, Marur T, Ertem AD, \u00d6zkuo K, Akk\u00c2n Splenic artery and relation between the tail of the pancreas and spleen in a surgical anatomical view. Karadeniz T\u00c2p Dergisi. 1996;9(2):103\u2013107.<\/li>\n<li style=\"text-align: justify;\">Herald Ellis. Clinical Anatomy. Blackwell publications. 2002;110-13p.<\/li>\n<li style=\"text-align: justify;\">Marecki B . The formation of the proportions of the liver, spleen and kidneys in the fetal ontogenesis. Z Morphol Anthropol. 1989;78(1):117\u2013132.<\/li>\n<li style=\"text-align: justify;\">Jeptha R. Hostetler, G.Adolph Ackerman. Lymphopoiesis and lymph node histogenesis in the embryonic and neonatal rabbit, American Journal of Anatomy, 1969:124(1);57-75.<\/li>\n<li style=\"text-align: justify;\">Hansen K, Sung CJ, Huang C, Pinar H, Singer DB, Oyer CE. Reference values for second trimester fetal and neonatal organ weights and measurements. Pediatr Dev Patho. 2003;l 6(2):160\u2013167.<\/li>\n<li style=\"text-align: justify;\">Singer DB, Sung CJ, Wigglesworth JS. Fetal growth and maturation: with standards for body and organ development. In: Wigglesworth JS, Singer DB (eds) Textbook of fetal and perinatal pathology, vol 1. Blackwell, Boston, 1991; pp 11\u201347.<\/li>\n<\/ol>\n<p style=\"text-align: justify;\">\n\t\t\t <div class=\"promo1\" style=\"background-color:#f7f7f7; border-color: #6b0e00 #e8e6e6 #e8e6e6;\">\n             \t <span style=\"color: #800000;\"><strong>Cite this article:<\/strong><\/span> Kuntal Vashishtha, Vinayak Gaur, Kanchan Kapoor. MORPHOMETRIC STUDY OF HUMAN FOETAL SPLEEN: A STUDY FROM NORTH-INDIA. Int J Anat Res 2018;6(4.3):5983-5988.\u00a0<strong>DOI:\u00a0<\/strong>10.16965\/ijar.2018.390\u00a0 \n             <\/div>\t\n\t\t\n","protected":false},"excerpt":{"rendered":"<p>Type of Article:\u00a0\u00a0Original Research Volume 6; Issue 4.3 (December 2018) Page No.:\u00a05983-5988 DOI:\u00a0https:\/\/dx.doi.org\/10.16965\/ijar.2018.390 MORPHOMETRIC STUDY OF HUMAN FOETAL SPLEEN: A STUDY FROM NORTH-INDIA Kuntal Vashishtha *1, Vinayak Gaur 2, Kanchan Kapoor 3. *1 Assistant Professor Anatomy, Dr. Y.S. Parmar Govt. medical college Nahan, Himachal Pradesh, India. 2 Assistant Professor Anatomy,J.L.N. medical college, Ajmer, Rajasthan, India.<br \/><a class=\"moretag\" href=\"https:\/\/www.ijmhr.org\/IntJAnatRes\/ijar-2018-390\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/1625"}],"collection":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/comments?post=1625"}],"version-history":[{"count":1,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/1625\/revisions"}],"predecessor-version":[{"id":1646,"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/pages\/1625\/revisions\/1646"}],"wp:attachment":[{"href":"https:\/\/www.ijmhr.org\/IntJAnatRes\/wp-json\/wp\/v2\/media?parent=1625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}